Antonio Possolo

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2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and related chemicals induce cytochrome P450 1A (CYP1A) gene expression and, at sufficient exposures, cause toxicity. Human health risks from such exposures are typically estimated from animal studies. We tested whether animal models predict human sensitivity by characterizing CYP1A gene expression in cultures of(More)
In 1994, the leadership 1 of the US Biometric Consortium asked a series of questions to the automated human recognition (" biometrics ") community revolving around the issues of repeatability and reproducibility of measurements in performance testing. Although we have made significant progress in our understanding, these issues have not been totally(More)
The theory and practice of estimationof binary Markov random fields on lattices is reviewed and advanced. The natural objects of inference are the local conditional distributions, which define an exponential family owing to the equivalence between Markov and Gibbs random fields. Maximumlikelihoodestimation generally is impracticable. Methods of asymptotic,(More)
This introduction to the R package alphashape3d is a (slightly) modified version of La-farge, Pateiro-López, Possolo, and Dunkers (2014), published in the Journal of Statistical Software. This work presents the implementation in R of the α-shape of a finite set of points in the three–dimensional space R 3. This geometric structure generalizes the convex(More)
We fit a two-parameter Weibull regression model by maximum likelihood estimation (MLE) to filtered surface roughness data. These data were acquired with scanning confocal laser microscopy performed on aluminium alloy AA 5754-O surfaces that were subjected to a range of plastic strain intensities in three different in-plane strain modes. Noting that one of(More)
—Energy Harvesting (EH) refers to the process of capturing and storing energy from external sources or ambient environment. Kinetic energy harvested from the human body motion seems to be one of the most convenient and attractive solution for wearable wireless sensors in healthcare applications. Due to their small size, such sensors have a very limited(More)
Pooling information from multiple, independent studies (meta-analysis) adds great value to medical research. Random effects models are widely used for this purpose. However, there are many different ways of estimating model parameters, and the choice of estimation procedure may be influential upon the conclusions of the meta-analysis. In this paper, we(More)