Antonio Mastroianni

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The dopamine pathway and especially the dopamine receptors 1 and 2 (DRD1 and DRD2) are implicated in the regulation of mothering in rats. Evidence for this in humans is lacking. Here, we show that genetic variation in both DRD1 and DRD2 genes in a sample of 187 Caucasian mothers predicts variation in distinct maternal behaviors during a 30-min mother-infant(More)
BACKGROUND Inflammation represents an early and key event in the development of both the cutaneous psoriasis and psoriatic arthritis. Compelling evidences indicate that the production of TNF-alpha plays a central role in psoriasis by sustaining the inflammatory process in the skin as well as in the joints. Among the multiple effects produced by TNF-alpha on(More)
La crescente complessità dei sistemi sanitari, accompagnata dalle numerose innovazioni della tecnologia biomedica, ha contribuito negli ultimi anni a un sovrautilizzo della diagnostica di laboratorio. Il recente Report dell’Institute of Medicine (IOM) Improving Diagnosis in Health Care si occupa anche di Medicina di Laboratorio e conclude che il processo(More)
Clinical research is at a cross-roads of sustainability due to the current cost of development, amount of regulation, and irrational use of medicine. There are also too many silos in clinical research and development, post-marketing safety, as well as a lack of standards, and effective communication. This paper covers the future of pharmacovigilance and(More)
Toscana virus (TOSV) is a Phlebotomus-transmitted RNA virus and a frequent cause of human meningitis and meningoencephalitis in Southern Europe during the summer season. While evidence for TOSV-related central nervous system (CNS) cases is increasing, little is known about the host defenses against TOSV. We evaluated innate immune response to TOSV by(More)
'impiego delle immunoglobuline endovena (IVIG) nell'anemia emolitica autoimmune (AIHA). Incontro nella terra dei Medici. Impiego clinico delle immunoglobuline endovena: presente e futuro. The high lysability by LAKs of colon carcinoma cells resistant to Doxorubicin is associated with a high expression of ICAM1, LFA3, NCA and a less-differentiated phenotype.(More)
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