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BACKGROUND Laparoscopic surgical procedures are being performed in pregnant women with increasing frequency. Maternal-fetal physiologic changes occurring during intraabdominal carbon dioxide insufflation are poorly understood, and maternal-fetal safety is of concern during carbon dioxide pneumoperitoneum. A previous pilot study using end-tidal carbon(More)
OBJECTIVES To evaluate podotrochlear bursa (navicular bursa) endoscopy as a diagnostic technique in horses and to correlate observations to radiographic and pathologic findings. STUDY DESIGN Descriptive study. SAMPLE POPULATION Seventeen equine cadaver forelimbs. METHODS Five standard radiographic views of the navicular region and a bursographic study(More)
OBJECTIVE To determine characteristics, incidence rate, and possible associations with selected demographic characteristics of catastrophic musculoskeletal injuries (CMIs) in Thoroughbred racehorses. ANIMALS 76 Thoroughbreds with CMIs. PROCEDURES Incidence rates of CMIs during racing or training were calculated with number of CMIs as the numerator and(More)
OBJECTIVE To evaluate clinical variables, regional concentrations, and pharmacokinetics of vancomycin in the synovial fluid of distal forelimb joints of horses after IV regional limb perfusion. ANIMALS 6 horses. PROCEDURE Vancomycin was administered via IV regional limb perfusion to the distal portion of the forelimbs of anesthetized horses. Drug (300(More)
Regional limb perfusion involves administration of an antimicrobial solution into the vasculature of a selected portion of the limb that has been isolated from the systemic circulation by controlled application of a tourniquet. The technique provides high antimicrobial concentrations in the region of interest and greatly contributes to the elimination of(More)
OBJECTIVE To determine the prevalence and severity of osteoarthritis in the metacarpophalangeal joints of Thoroughbred racehorses via development and validation of a quantitative macroscopic evaluation system. SAMPLE POPULATION Metacarpophalangeal joints from 50 Thoroughbred racehorses. PROCEDURES Joints were collected from horses that died or were(More)
OBJECTIVE To evaluate the clinical effects and pharmacokinetics of vancomycin in plasma and synovial fluid after intraosseous regional limb perfusion (IORLP) in horses and to compare results with those obtained after IV regional limb perfusion (IVRLP). ANIMALS 6 horses. PROCEDURES 1 forelimb of each horse received vancomycin hydrochloride (300 mg in 60(More)
OBJECTIVE To evaluate the performance of a chemiluminescent endotoxin activity assay in horses with colic and healthy horses. ANIMALS 20 horses with colic and systemic inflammatory response syndrome (SIRS group), 8 horses with colic with no SIRS (NSIRS group), and 20 healthy horses. PROCEDURES Venous blood was collected into EDTA blood collection tubes(More)
OBJECTIVE To study osteoarthritis in the equine medial femorotibial (MFT) joint after a single traumatic injury. ANIMALS 10 mature horses. PROCEDURE In vitro explant cultures were used to determine injury threshold for stifle joint cartilage. Contusive impacts were applied to the medial femoral condyle (MFC), and horses were followed for 84 (n = 5) and(More)
In this study, we aimed to define the effects of anesthesia and surgery on the resting energy expenditure of horses in experimental conditions. Six horses were used in a longitudinal study with 2 study periods: before and after anesthesia and surgery. Every horse underwent a standard 90-min ventral midline exploratory laparotomy. Oxygen uptake (VO2) and(More)