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BACKGROUND AND PURPOSE There is a need for empirical studies to define criteria for vascular cognitive impairment (VCI) subtypes. In this paper, we report the predictive validity of a subtype classification scheme based on clinical and radiographic features. METHODS Nine Canadian memory clinics participated in the Consortium to Investigate Vascular(More)
Android malware has emerged in the last decade as a consequence of the increasing popularity of smartphones and tablets. While most previous work focuses on inherent characteristics of Android apps to detect malware, this study analyses indirect features to identify patterns often observed in malware applications. We show that modern Machine Learning(More)
The workload on a cluster system can be highly variable, increasing the difficulty of balancing the load across its nodes. And the general rule is that high variability leads to wrong load balancing decisions taken with out-of-date information and difficult to correct in real-time during applications execution.In this work the workload variability is(More)
Helicobacter pylori adhere to Kato III and Hela S3 cells in monolayer cultures. To explore whether cell surface glycoconjugates on these two cell lines mediate binding of H. pylori, various carbohydrates, glycoproteins, and glycolipids were tested to inhibit H. pylori cell adhesion. The adhesion was measured (i) with a urease-based assay and (ii) by cells(More)
UNLABELLED Gamma aminobutyric acid (GABA)A receptor modulators constitute the majority of clinically used sedative-hypnotics. These compounds have the capacity to initiate and maintain sleep, but decrease REM sleep and delta activity within NREM sleep. In order to avoid such sleep adverse effects, the development of novel compounds remains of interest. (More)
Conditions of marked and long-lasting hypothermia have been shown to increase the formation of micronucleated polychromatic erythrocyte (MNPCE) in mouse bone-marrow. Stimulation of erythropoiesis as a consequence of anoxic conditions associated with decreased body temperature has been suggested as a possible mechanism for hypothermia-induced micronucleus(More)
BACKGROUND The Consortium to Investigate Vascular Impairment of Cognition (CIVIC) is a Canadian, multi-centre, clinic-based prospective cohort study of patients with Vascular Cognitive Impairment (VCI). We report its organization and the impact of diagnostic criteria on the study of VCI. METHODS Nine memory disability clinics enrolled patients and(More)
BACKGROUND AND PURPOSE Empirical studies to clarify the outcomes in Vascular Cognitive Impairment (VCI) are needed. We compared cognitive, functional, and behavioural outcomes in patients with VCI to patients with no cognitive impairment (NCI), and Alzheimer's disease (AD). METHODS Secondary analysis of the Consortium to Investigate Vascular Impairment of(More)
Cluster heterogeneity increases the difficulty of balancing the load across the system nodes. Although the relationship between heterogeneity and load balancing is difficult to describe analytically, in this paper an exhaustive analysis of the effects of this system feature on load balancing algorithms performance is presented. Considering the performed(More)