Antonio Dellavalle

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BACKGROUND The use of drug-eluting stents (DES) in patients at high risk of bleeding or thrombosis has not been prospectively studied; limited data are available in patients who have a low restenosis risk. OBJECTIVES This study sought to compare a hydrophilic polymer-based, second-generation zotarolimus-eluting stent (ZES) with a unique drug fast-release(More)
BACKGROUND Tissue proliferation is almost invariably observed in recurrent lesions within stents, and ACE, a factor of smooth muscle cell proliferation, may play an important role. Plasma ACE level is largely controlled by the insertion/deletion (I/D) polymorphism of the enzyme gene. The association among restenosis within coronary stents, plasma ACE level,(More)
OBJECTIVES The aim of the study was to compare randomly assigned primary angioplasty and accelerated recombinant tissue plasminogen activator (rt-PA), in patients with "high-risk" inferior acute myocardial infarction (ST-segment elevation in the inferior leads and ST-segment depression in the precordial leads). BACKGROUND The ST-segment depression in the(More)
BACKGROUND The lower prevalence of ventricular late potentials (LPs) in signal-averaged electrocardiograms (SAECG) observed in patients (pts) treated with systemic thrombolysis, as compared with SAECGs in conventionally treated pts, has been attributed to the patency of the infarct-related artery. Mechanical reperfusion, achieved by means of either primary(More)
OBJECTIVE To test whether very early resumption of ambulation after femoral cardiac catheterisation is feasible and safe in patients with stable symptoms. DESIGN Prospective study in a selected group of men and women undergoing elective cardiac catheterisation, with next day physical inspection. SETTING Inpatient study. SUBJECTS Two hundred(More)
Nineteen consecutive procedures of coronary stenting were attempted in 70 consecutive patients (27%) with evolving myocardial infarction due to threatened vessel reocclusion after primary (16 cases) or rescue (3 cases) angioplasty. Two patients were in cardiogenic shock. Stent delivery was successful in 18 patients, with a Thrombolysis in Myocardial(More)
Radiation exposure of cardiac catheterization laboratory staff is a known occupational hazard, and efforts are made to obtain dose levels which are "as low as reasonably achievable". This study assessed the reduction in staff radiation exposure using cine framing at 12.5 f s-1 during coronary cineangiography, instead of 25 f s-1. Thermoluminescent(More)
BACKGROUND One-hundred consecutive procedures of elective coronary angioplasty were attempted in 95 patients, in the absence of any surgical stand-by. All patients had angina and/or signs of inducible ischemia. METHODS All patients and attending physicians were informed that no surgical coverage was available, and gave their consent. The choice was made(More)
BACKGROUND The cardiac catheterization laboratory (CCL) of our hospital is the only facility for invasive cardiology in a large district. No cardiac surgery is carried out in our hospital at present, the nearest facility being approximately 50 miles away. METHODS Over a period of 2 years we recommended percutaneous transluminal coronary angioplasty (PTCA)(More)
BACKGROUND The purpose of this study was to assess the current care of elderly patients with non-ST-elevation acute coronary syndrome (ACS), with particular regard to the rate of use of antiplatelet drugs and the type of strategy, aggressive or conservative, in a population of consecutive patients admitted to 76 Coronary Care Units in Italy. METHODS(More)