Antonio Correa

Learn More
Three new antitumour drugs containing two 5-fluorouracil moieties at both ends of the structure and a two amide bond linker were synthesized. Appropriated bis-acetal were reacted with two equivalents of 5-FU to afford the desired compounds. These drugs were evaluated for their ability to induce myogenic maturation in vitro on human rhabdomyosarcoma cells in(More)
Epigenetic mechanisms such as DNA methylation and histone modification are important in stem cell differentiation. Methylation is principally associated with transcriptional repression, and histone acetylation is correlated with an active chromatin state. We determined the effects of these epigenetic mechanisms on adipocyte differentiation in mesenchymal(More)
This thesis explores the difference in adoption patterns of water recharge well technology in Mexico City both by local entities and the central city government. The research finds that this technology, originally designed by the central city with the stated purpose of aiding aquifer recharge, was adopted by local entities driven by concerns over flood(More)
  • 1