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OBJECTIVE To assess the feasibility and activity of a neoadjuvant treatment combining a luteinizing hormone-releasing hormone (LHRH)-analogue, estramustine and docetaxel before radical retropubic prostatectomy (RRP) in patients with high-risk prostate cancer. PATIENTS AND METHODS High-risk patients were defined as clinical stage > or =T3 and/or a(More)
Clinical manifestations of acute appendicitis are variegated and urologic symptoms may be the first manifestation of the disease. In 1985 we reported on 2 cases of acute appendicitis who presented with irritative bladder symptoms. Here we describe 2 new cases come to our observation because of hematuria and irritative bladder symptoms. A brief review of the(More)
The description of a gesture requires temporal analysis of values generated by input sensors and does not fit well the observer pattern traditionally used by frameworks to handle user input. The current solution is to embed particular gesture-based interactions, such as pinch-to-zoom, into frameworks by notifying when a whole gesture is detected. This(More)
The C++ language has only a limited runtime type information system , which doesn't provide full reflection capabilities. We present a general mechanism to support reflection, exploiting template metaprogramming techniques. Two solutions are presented: a static one where metaclass information is only available at compile time to produce class specific code;(More)
AIM The efficacy of prostaglandin E1 (PGE1)-intracavernous injection (ICI) therapy for erectile dysfunction (ED) after non-nerve-sparing (NNS) radical pelvic surgery depends on patient compliance. The purpose of this study was to verify the utility of sexual counseling in ICI in terms of treatment efficacy, compliance, and dropout rate. METHODS In this(More)
" Computers are useless: they can only give answers " – Pablo Picasso – Abstract PiQASso is a Question Answering system based on a combination of modern IR techniques and a series of semantic filters for selecting paragraphs containing a justifiable answer. Semantic filtering is based on several NLP tools, including a dependency-based parser, a POS tagger,(More)
BACKGROUND The objective of the current study was to identify independent clinical and pathologic variables that were predictive of lymph node involvement in patients with squamous cell carcinoma of the penis in a multicenter series with the intent to select patients who were suitable to undergo immediate inguinal lymphadenectomy. METHODS Data were(More)
Gestural interfaces allow complex manipulative interactions that are hardly manageable using traditional event handlers. Indeed, such kind of interaction has longer duration in time than that carried out in form-based user interfaces, and often it is important to provide users with intermediate feedback during the gesture performance. Therefore, the gesture(More)
We present a framework for code generation that allows programs to manipulate and generate code at the source level while the joining and splicing of executable code is carried out automatically at the intermediate code/VM level. The framework introduces a data type Code to represent code fragments: methods/operators from this class are used to reify a(More)