Antonio Ciccarone

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In neurofibromatosis type 1 (NF1), Central Precocious Puberty (CPP) occurs almost invariably in association with optic pathway tumors, usually pilo-cytic astrocytoma. 1 However, at times the aetiology remains undefined. 2 On the other hand, in the general population CPP develops due to an underlying hy-pothalamic hamartoma in up to 10% of patients. 3 To the(More)
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