Antonio Alvarado

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n engl j med 366;17 nejm.org april 26, 2012 1648 The clinicians found that the patient’s international normalized ratio was essentially normal with a range of 1.1 to 1.2, but the prothrombin time was slightly prolonged (range, 13.1 to 14.2 seconds [reference range, 11.0 to 13.3]). Her severe thrombocytopenia, slightly prolonged prothrombin time, and normal(More)
Two hundred and five women participating in a five-year clinical trial of NORPLANT and NORPLANT-2 were interviewed about their contraceptive and reproductive history, sources of information and knowledge of NORPLANT, experiences using the method, and the impressions of friends and family about the method. The most common reasons for trying the implants were(More)
BACKGROUND There are no chilean reports on gallstone dissolution using oral medications. AIM To measure the proportion of asymptomatic adult women eligible for gallstone dissolution therapy and to test the effectiveness and tolerance of lovastatin for this purpose. SUBJECTS AND METHODS Three hundred fifty six women working at health care institutions(More)
BACKGROUND/AIMS Intrahepatic cholestasis of pregnancy is a rare disease of unknown etiology, with a strikingly higher prevalence in Chile than in most other countries. Although several studies suggest that a genetic predisposition is involved in the pathogenesis, no genetic disease-marker has so far been identified. Using a recently developed HLA-genotyping(More)
Tacrolimus and sirolimus are commonly used maintenance immunosuppressants in kidney transplantation. As their effects on immune cells and allograft molecular profiles have not been elucidated, we characterized the effects of tacrolimus to sirolimus conversion on the frequency and function of T cells, and on graft molecular profiles. Samples from renal(More)
Capronor, a single-capsule, biodegradable, subdermal contraceptive that releases levonorgestrel over a 12- to 18-month period, has been evaluated in 48 healthy women, ages 18 to 40 years. Sixteen participants received a 2.5 cm capsule (12 mg of levonorgestrel), and 32 received a 4.0 cm capsule (21.6 mg of levonorgestrel). Serum levonorgestrel levels were(More)
Breast cancer is one of the most common cancer in women worldwide. Appropriate animal models are essential to improve the diagnosis and therapy for this disease. This study proposed to evaluate the effects of exercise training on the Ki-67 proliferation index (Ki-67 PI) in mammary tumors chemically-induced in a recognized rat model by immunohistochemistry.(More)
A prospective survey was carried out in 205 males and 667 females who had their gallbladder removed for gallstone disease during 1989 at a general hospital in Chile. Females had a greater prevalence of disease with an earlier appearance of symptoms leading to surgery at a younger age. In contrast, males developed a more aggressive form of the disease, with(More)
The aim of this study was to know if cholecystectomy rates have decreased in young women, considering that these rates have decreased in the last years in the general chilean population. The frequency of previous cholecystectomy was compared in 1582 women aged 23.9 +/- 5.8 years admitted to a maternity for delivery between 1985 and 1986 and 4943 women aged(More)
The purpose of this study was to evaluate the effect of verapamil administration on Human Fetuses in High Risk Pregnancies (FHRP) by Proton Magnetic Resonance Spectroscopy (HMRS) after Lactate identification. Two HMRS studies were performed on a 1.5 Tesla system using the body RF coil: the first one was done between 30-31 weeks of gestation and the second(More)
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