Antoni Sitges-Serra

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Hyperparathyroidism associated with renal failure is due to chronic parathyroid stimulation by hypocalcemia, which, in turn, results from hyperphosphatemia and low circulating 1,25(OH)2D3. If prophylactic measures and medical treatment of hyperparathyroidism fail, parathyroidectomy should be performed to prevent the progression of bone disease. Resolution(More)
BACKGROUND The aim was to evaluate the factors determining preoperative renal dysfunction in patients with obstructive jaundice. METHODS In a prospective cross-sectional observational study, 63 patients, 27 with benign and 36 with malignant obstructive jaundice, were investigated at admission and compared with 25 healthy control subjects. Variables(More)
BACKGROUND Sacral nerve stimulation (SNS) has better results and safety than other surgical procedures for faecal incontinence. This prospective study assessed the clinical effectiveness and costs of SNS at a single centre. METHODS Patients who had experienced one or more episodes of faecal incontinence were studied for up to 5 years by continence diary,(More)
BACKGROUND Many operative procedures involve suturing healthy, previously nontraumatized tissues. The present study was done to investigate the wound breaking strength and healing after suturing noninjured tissues. STUDY DESIGN A new experimental model of muscluloaponeurotic suture in the mouse is described and used to investigate the scar breaking(More)
OBJECTIVE To evaluate the influence of internal drainage on status of nutritional markers in patients with obstructive jaundice. DESSING: Prospective longitudinal study. SETTING University hospital, Spain. SUBJECTS 39 patients with obstructive jaundice (18 benign and 21 malignant obstructions). INTERVENTIONS Nutritional state was assessed before and(More)
Colonic perforation is the second most common complication of colonic neoplasms and is associated with an elevated morbidity and mortality. We undertook a two-centre retrospective analysis of 378 colonic neoplasms seen from 1978 to 1985. Thirty-six patients (9.5%) presented with a perforated colonic carcinoma. Two-thirds had a past history suggesting(More)
OBJECTIVES the aim of this study was to assess the severity and type of nutritional deficiencies observed in patients with benign and malignant obstructive jaundice (OJ). METHOD in this prospective cross-sectional study 51 patients with OJ (21 with benign and with 30 malignant obstruction) were investigated. Nutritional status was assessed by(More)
OBJECTIVE To assess the immediate and long-term clinical results of 2 different surgical procedures for the treatment of asymmetrical multinodular goiter (AMG). BACKGROUND Half of the patients presenting with a single benign thyroid nodule have contralateral subclinical disease. There is a controversy whether these patients should be treated with(More)
BACKGROUND Anorexia is a frequent finding in patients with biliary obstruction (BO). This study investigates the role of biochemical and hormonal factors in the pathogenesis of reduced food intake in BO and the effects of internal biliary drainage. STUDY DESIGN Sixty-two patients with BO were prospectively investigated. Transaminases, amylase,(More)