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Brain- derived neurotrophic factor (BDNF) is linked to neurodegenerative diseases (e.g. Alzheimer disease and Parkinson disease) which are often characterized by olfactory impairment. A specific single nucleotide polymorphism of the BDNF gene, the Val66Met, modulates intracellular trafficking and activity-dependent secretion of BDNF protein. The aim of this(More)
Prospective studies that incorporate both gene testing and a variety of ethnic, clinical, pharmacological, and environmental variables, along with age, sex, and body weight, will be required to demonstrate the real safety, cost-effectiveness, and feasibility of individualized dosing regimens according to the statistical models for warfarin dose calculation.(More)
Biobanks play a crucial role in "-Omics" research providing well-annotated samples to study major diseases, their pathways and mechanisms. Accordingly, there are major efforts worldwide to professionalize biobanks in order to provide high quality preservation and storage of biological samples with potentially greater scientific impact. Biobanks are an(More)
INSTRUMENTS FOR EVALUATION OF MEMORY ABILITIES IN CHILDREN Summary. Objectives. This is a review of the more relevant instruments to measure memory abilities of children and adolescents. The strengths, limitations and future developments of these instruments are discussed. Contents. Memory disturbances are present in developing individuals as a consequence(More)
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