Antonella Litta

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AIM To evaluate the efficacy and safety of the augmentation of clozapine with aripiprazole in patients with treatment-resistant schizoaffective and psychotic bipolar disorders in a retrospective manner. Pharmacodynamic and pharmacokinetic interactions between the two drugs were also investigated. PATIENTS Three men and 4 women (median age 36 and 40 years,(More)
AIM The authors present the cases of three bipolar patients who developed Neuroleptic Malignant Syndrome (NMS) after antipsychotic treatment, both typical and atypical, focusing on relationship between NMS and catatonia. METHODS In all three cases, administration of antipsychotics has been stopped at once, when fever and autonomic disturbances occurred. A(More)
BACKGROUND Neuroleptic malignant syndrome (NMS) represents an iatrogenic form of malignant catatonia, and simple catatonia has been shown to predispose to NMS. OBJECTIVE The authors present the case of a bipolar patient with catatonic features who developed NMS after receiving haloperidol. METHOD Supportive therapy, including rehydration, electrolyte(More)
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