Antonella Afeltra

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PURPOSE Inflammation has been shown to play a key role in epilepsy, and may also affect both the iron status and metabolism. Consequently, a relationship between iron metabolism and neuronal excitability and seizures could be expected. METHODS We aimed at characterizing in 37 adult patients affected by focal epilepsy during the interictal period serum(More)
In this paper, we report our experience in the development of a system for automatic acquisition of Immuno-Fluorescence Assay (IFA) images. We focus on two basic issues. Firstly, we determine an autofocus function that can deal with photobleaching, a physical phenomenon affecting automatic acquisition of IFA images, and present a set of experiments on real(More)
The authors assessed the prevalence of neuropsychiatric manifestations occurring in patients with systemic lupus erythematosus (NPSLE), according to the American College of Rheumatology standardized definitions for NPSLE, and evaluated the relationship between NPSLE and antiphospholipid antibodies. Sixty-one consecutive SLE patients were studied.(More)
INTRODUCTION The diagnostic, predictive and prognostic role of anti-cyclic citrullinated peptide (CCP) antibodies in rheumatoid arthritis (RA) patients is widely accepted. Moreover, detection of these antibodies in subjects presenting with undifferentiated arthritis (UA) is associated with a significant risk to develop the disease. On the other hand,(More)
BACKGROUND To compare tumor necrosis in hepatoma induced in rats by a single percutaneous injection of ethanol (PEI) or acetic acid (PAI). METHODS BW7756 hepatomas of 1 mm3 were implanted in the liver of 40 male healthy rats. After 14 days, the 36 surviving rats were treated, in a single session, by ultrasound-guided injection of 300 microl of 95% ethanol(More)
INTRODUCTION In recent years, there has been an increased demand for computer-aided diagnosis (CAD) tools to support clinicians in the field of indirect immunofluorescence. To this aim, academic and industrial research is focusing on detecting antinuclear, anti-neutrophil, and anti-double-stranded (anti-dsDNA) antibodies. Within this framework, we present a(More)
  • Domenico Pe Margiotta, Marta Vadacca, Luca Navarini, Fabio Basta, Antonella Afeltra
  • 2016
The difficulty in identifying, differentiating and expressing emotions is a neuropsychological condition called alexithymia. During the last years it has grown the interest of scientific community for alexithymia, in particular in chronic conditions. Crescent literature data demonstrated that a considerable number of SLE patients present difficulty not only(More)
INTRODUCTION The objective of the present study was to compare QUANTA Flash dsDNA, a chemiluminescent immunoassay (CIA) on the BIO-FLASH, a rapid-response chemiluminescent analyzer, to three other anti-dsDNA antibody assays and to Crithidia luciliae indirect immunofluorescence test (CLIFT). METHODS In the first part of the study, 161 samples, 61 from(More)
Whether tumor necrosis factor-alpha (TNFα) caused beneficial or detrimental cardiovascular effects remains poorly defined. Anti-TNFα agents improved cardiac end points in chronic rheumatic diseases characterized by progressive deterioration of cardiac function. In contrast, anti-TNFα agents did not always improve but actually worsened cardiac function in(More)
Lavori in Extenso 1. Plasma and CSF tryptophan in cancer anorexia. 2. Eating behavior and adherence to dietary prescriptions in obese adult subjects treated with 5-hydroxytryptophan. 3. Cytokines, tryptophan and anorexia in cancer patients before and after surgical tumor ablation. 4. Comparative effects of arginine and other amino acid deprivation on in(More)