Anton R Shumakov

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The goal of the work was a study of the effect of exhaustive weightlifting exercise on prolonged changes in the physiological and biochemical variables characterizing the functional state of skeletal muscles. An exercise accentuated at muscles of the hip surface gave rise to a significant increase of the blood lactate concentration, which indicated that(More)
It is known that a closure of ATP sensitive (mitoKATP) or BK-type Ca(2+) activated (mitoKCa) potassium channels triggers opening of the mitochondrial permeability transition pore (MPTP) in cells and isolated mitochondria. We found earlier that the Tl(+)-induced MPTP opening in Ca(2+)-loaded rat liver mitochondria was accompanied by a decrease of(More)
The report deals with a molecular-genetic study of human pepsinogen A (PGA) genetic locus. EcoRI, HindIII and BamH 1 restriction endonuclease technique were employed. The investigation involving 58 patients with stomach cancer (SC) and 18 healthy donors failed to identify any significant PGA genetic restructuring in the blood of healthy donors. However, DNA(More)
Microsatellite instability (MIN) of human genome, i.e. instability of very short (1-5 nt) DNA tandem repeats, points to a deficiency in the mismatch repair system (MMR). To investigate the role of MMR in sporadic and hereditary carcinogenesis in the gastrointestinal tract, four types of carcinomas were compared: sporadic (GC), familial (FGC) gastric(More)
In many cases of stomach disease, specific epithelial changes of the mucous membrane have already been detected and staged in the past. An attempt has been made in this study to assess with a more up-to-date approach the data concerning the possible molecular biological mechanisms of tumor proliferation in stomach epithelial cells.
The effect of exhaustive weightlifting exercise (WE) on the time-related changes in performance capacity was studied along with measuring several physiological and biochemical variables during exercise. The work performed decreased soon after the start of exercise and stabilized after reducing the amount of weight used (40-10% 1RM). The maximal amplitude of(More)
The aim of this study was to examine the effect of exhaustive weightlifting exercise on electrical and biochemical variables and performance capacity in young male subjects. The onset of exercise (80-50% 1RM) was associated with a decrease in the amount of work performed, which was followed by a steady performance capacity at 40-10% 1RM. There were no(More)
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