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PURPOSE The authors studied the indocyanine green (ICG) videoangiography findings of central serous chorioretinopathy (CSC) in older adults. BACKGROUND Central serous chorioretinopathy in older adults may be confused with the exudative forms of age-related macular degeneration (AMD) because the two entities may have similar ophthalmoscopic and fluorescein(More)
BACKGROUND To report long-term intraocular tolerance of perfluorohexyloctane (F(6)H(8)). METHODS F(6)H(8) was used as an endotamponade in 18 patients (9 male and 9 female) with a median age of 65 years (range, 14-82 years) and complicated pathologic conditions of the inferior fundus: rhegmatogenous retinal detachment (17 patients) and tractional retinal(More)
The rapid loss of skeletal-muscle protein during starvation and after denervation occurs primarily through increased rates of protein breakdown and activation of a non-lysosomal ATP-dependent proteolytic process. To investigate whether protein flux through the ubiquitin (Ub)-proteasome pathway is enhanced, as was suggested by related studies, we measured,(More)
The rapid atrophy of skeletal muscles upon fasting or denervation is due largely to an increased rate of protein breakdown. Blocking the lysosomal or the Ca(2+)-dependent pathways did not prevent increased proteolysis in muscles from fasted animals or following denervation. In contrast, upon food deprivation, the nonlysosomal ATP-dependent process increased(More)
AIM The current accepted standard treatment for neovascular age-related macular degeneration (AMD) consists of antivascular endothelial growth factor agents including ranibizumab and bevacizumab. The aim of the study was to examine whether bevacizumab is inferior to ranibizumab with respect to maintaining/improving visual acuity. METHODS In this(More)
PURPOSE Exudative age-related macular degeneration (AMD) is one of the most common causes of severe visual loss. Both environmental and genetic factors, such as the complement factor H (CFH) 402H allele, have been associated with AMD. Recently, the HTRA1 -625A allele was identified as a novel risk marker in both a North American and a Chinese population.(More)
BACKGROUND The purpose of this study was to investigate and identify predictors for idiopathic macular hole persistence after pars plana vitrectomy with dye-assisted internal limiting membrane peeling. METHODS In a retrospective case series, 160 eyes underwent identical vitreoretinal procedures performed by the same surgeon. Baseline characteristics and(More)
PURPOSE To investigate the electrophysiological findings of a multifocal ERG in multiple evanescent white dot syndrome (MEWDS). METHODS Multifocal electroretinograms (mf-ERG) were recorded from four patients with MEWDS. The stimulus array consisted of 61 hexagons and was presented according to a binary m-sequence. We analyzed the N1- and P1-wave(More)
  • B Feigl, A Haas
  • 2001
BACKGROUND In comparison to full-field ERG a multifocal ERG (mf-ERG) provides functional mapping of the central retina and detection of more localised defects. Central areolar choroidal dystrophy is an autosomal dominant inherited disorder with central atrophy of the choriocapillaries, the retinal pigment epithelium (RPE) and the photoreceptors. Full-field(More)
OBJECTIVE This study aimed to determine the effect of external beam radiation therapy on choroidal neovascularization (CNV) secondary to age-related macular degeneration (AMD). DESIGN The study design was a nonrandomized clinical trial with an historic control group. PARTICIPANTS A total of 91 patients were treated with external beam radiation. These(More)