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Recommended by Hikmet Sari We investigate the use of a linear precoded orthogonal frequency division multiplexing (LP-OFDM) waveform for high-data-rate ultra-wideband (UWB) systems. This waveform applied for the first time to UWB applications is an evolution of the multiband OFDM (MB-OFDM) solution supported by WiMedia-MBOA (MultiBand OFDM Alliance). The(More)
Ultra-wideband (UWB) is a fast technology that has recently attracted considerable interest in the research and standardization communities, due to its ability to provide high data rate at low cost and low power consumption. The objective of this thesis is to propose a new UWB system for high data rate wireless personal area network (WPAN) applications,(More)
According to the US Food and Drug Administration (FDA), if a drug product contains a drug substance that is chemically identical and is delivered to the site of action at the same rate and extent as another drug product, then it is equivalent and can be substituted (switchable) for that drug product. Methods used to define bioequivalence as stated by the(More)
OBJECTIVES To determine prospectively the temporal variations of cyclosporine-A lymphocyte maximum level, whole blood maximum concentration, and total lymphocyte count in patients with de novo kidney transplantation. MATERIALS AND METHODS Lymphocyte maximum level, whole blood maximum concentration, and total lymphocyte count were prospectively measured in(More)
BACKGROUND In subjects with end-stage renal disease (ESRD) undergoing hemodialysis, aortic pulse wave velocity (PWV) is increased independently of blood pressure level and mostly is a strong predictor of cardiovascular risk. Few studies on this subject have been performed in renal transplant patients. METHODS Aortic PWV was determined noninvasively in 106(More)
During the seventies, sporadic renal transplants were performed in few MESOT-region countries, mainly Turkey, Iran, Egypt, and Lebanon. Since the introduction of cyclosporine in the early eighties, transplantation has become the preferred therapeutic modality for end-stage renal failure. In 1986, the Islamic theologians (Al Aloma) issued what became known(More)
BACKGROUND Cardiovascular (CV) risk remains high in renal transplant patients despite a clear improvement conferred by transplantation. This risk is attributed mostly to recipient-related risk factors. Donor vascular characteristics, such as arterial stiffness, have been poorly investigated in this regard. METHODS Recipients of living-related (n = 75) and(More)
In subjects with renal disease, reduced renal function and increased arterial stiffness are significantly associated in cross-sectional studies. The relationship is independent of age, blood pressure (BP), and atherosclerosis. Because both variables are independent predictors of cardiovascular risk, time-dependent relationships between them are important to(More)
The nephrotoxic and extra-renal adverse effects associated with calcineurin inhibitor (CNI) therapies appear to have a negative impact on long-term graft survival. Several CNI minimization protocols have been recently studied. These protocols involve either early CNI avoidance or CNI withdrawal. CNI withdrawal strategies are associated with a significant(More)