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BACKGROUND Endothelial Microparticles (EMPs) are small vesicles shed from activated or apoptotic endothelial cells and involved in cellular cross-talk. Whether EMP immunophenotypes vary according to stimulus in Diabetes Mellitus (DM) is not known. We studied the cellular adhesion molecule (CAM) profile of circulating EMPs in patients with and without(More)
Angiotensin-II (Ang-II)-stimulated increases in nicotinamide adenine dinucleotide phosphate reduced (NADPH) oxidase activity and oxidative stress are known to play a key role in cardiac remodeling. Inhibition of isoprenylation and activation of small G proteins, such as Rac1, a component of NADPH oxidase, may mediate the antioxidant actions of(More)
Welcome to the second quarterly Department of Medicine newsletter. Although we put the last newsletter together barely three months ago, there is a wealth of new news from the Department. The Department continues to grow and members of the department continue to excel in clinical care, research, education, and service. It is truly impossible to capture all(More)
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