Anthony Stramaglia

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Several studies indicate that fibrin may play a functional role in inflammation by modulating a variety of cellular functions. We investigated the effect of fibrin on tissue factor (TF) production by blood mononuclear cells (MNC). Citrated human blood was recalcified and incubated at 37 degrees C for 1-4 h. The resulting clot was lysed by the addition of(More)
Activated protein C (APC) is a natural anticoagulant and inhibits thrombin generation by degrading factors Va and VIIIa. We evaluated the ability of APC to inhibit blood coagulation triggered by lipopolysaccharide (LPS)-stimulated [tissue factor (TF)-expressing] human mononuclear cells (MNCs) or umbilical vein endothelial cells (HUVECs). Using a plasma(More)
Cracker attack plans often include attempts to gain access to target local computing and networking resources via war dialed entry around firewall-protected gateways. This paper describes two methods for organizations to reduce this risk in environments where removal of unknown modems is not feasible. In particular, we outline a workstation-based war dial(More)
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