Anthony Schelleman

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Knowledge of renal blood flow is considered important in the management of critically ill patients with acute renal failure. Renal Doppler ultrasound has been used to estimate renal blood flow. Its accuracy, however, has not been formally assessed. Prospective blinded animal study. University physiology laboratory. Seven merino cross-ewes. We chronically(More)
INTRODUCTION Contrast-enhanced ultrasound (CEUS) is a new technique that might enable portable and non-invasive organ perfusion quantification at the bedside. However, it has not yet been tested in critically ill patients. We sought to establish CEUS's feasibility, safety, reproducibility and potential diagnostic value in the assessment of renal cortical(More)
Acute kidney injury (AKI) is common in critically ill patients and associated with important morbidity and mortality. Although alterations in renal perfusion are thought to play a causative role in the pathogenesis of AKI, there is, to date, no reliable technique that allows the assessment of renal perfusion that is applicable in the ICU. Contrast-enhanced(More)
BACKGROUND Terlipressin improves renal function in some patients with type-1 hepato-renal syndrome (HRS). Renal contrast-enhanced ultrasound (CEUS), a novel imaging modality, may help to predict terlipressin responsiveness. OBJECTIVES We used CEUS to estimate the effect of terlipressin on the renal cortical microcirculation in type-1 HRS. METHODS We(More)
BACKGROUND Contrast-enhanced ultrasonography (CEUS) is a novel imaging modality to estimate microvascular perfusion. We aimed to assess renal cortical microcirculatory changes by CEUS during pharmacologically or mechanically induced modifications of renal blood flow (RBF) in experimental animals. METHODS We implanted invasive transit-time Doppler flow(More)
Venous aneurysms of the superior mesenteric vein and portal vein are an uncommon occurrence and often an incidental finding. They can also be associated with hepatocellular disease and portal hypertension. We present CT and ultrasound findings of these entities. The management of venous aneurysms is generally conservative with serial imaging.
INTRODUCTION We used contrast-enhanced ultrasound (CEUS) to estimate the effect of an increase in mean arterial pressure (MAP) induced by noradrenaline infusion on renal microvascular cortical perfusion in critically ill patients. METHODS Twelve patients requiring a noradrenaline infusion to maintain a MAP more than 60 mmHg within 48 hours of intensive(More)
s are available online only, free of charge, at www.karger.com/doi/10.1159/000351231 Basel · Freiburg · Paris · London · New York · New Delhi · Bangkok · Beijing · Tokyo · Kuala Lumpur · Singapore · Sydney Selected Abstracts from the 31th International Vicenza Course on Critical Care Nephrology Vicenza, June 11–14, 2013 D ow nl oa de d by : 54 .7 0. 40 .1 1(More)
and wrists and a vascular purpura of the lower extremities. He was febrile to 39°C and had normal proximal and distal muscle strength in the upper and lower limbs. Magnetic resonance imaging and cerebrospinal fluid examination were normal. The nerve conduction speeds of the cubital, radial, sciatic and peroneal nerves were normal on the electromyogram.(More)
A 34-year-old Malaysian man presented with esophageal variceal bleeding, which was successfully treated with sclerotherapy. Investigations at that time showed evidence of portal hypertension with prominent portosystemic collateral vessels and splenomegaly. Hepatic synthetic function was normal. A liver biopsy revealed minimal fibrosis of nonspecific(More)