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Eight experienced male cyclists (C), eight well-trained male runners (R), and eight less-trained male noncyclists (LT) were tested under multiple cadence and power output conditions to determine: (1) if the cadence at which lower extremity net joint moments are minimized (cost function cadence) was associated with preferred pedaling cadence (PC), (2) if the(More)
'Mild cognitive impairment' (MCI) in older adults refers to a significant decline in memory function but not other cognitive functions. Pharmacological and non-pharmacological treatments for MCI are needed. The present randomized clinical trial tests the efficacy of a cognitive and behavioral treatment to improve memory performance and participants'(More)
BACKGROUND Physical function and strength decline with age and lead to limited mobility and independence in older adults. Alterations in mitochondrial function are thought to underlie numerous age-related changes, including declining physical ability. Recent studies suggest that systemic changes in bioenergetic capacity may be reported by analyzing(More)
A dual-task paradigm was used to determine the attentional demands of several postural control tasks in 16 older women (age, 71.5+/-3.4 years) and 14 young women (age, 25.5+/-2.4 years). Older women had slower verbal reaction times (VRT) compared with the younger women and increased reaction time more from a sitting to standing posture. Compared with the(More)
Traditional posturographic analysis and four statistical mechanics techniques were applied to center-of-pressure (COP) trajectories of young, older "low-fall-risk" and older "high-fall-risk" individuals. Low-fall-risk older adults were active 3 days per week in a cardiac rehabilitation program, while high-fall-risk older adults were diagnosed with perilymph(More)
Male cyclists (N = 8) and noncyclists (N = 8) pedaled under six randomly ordered cadences (50, 65, 80, 95, 110 rpm and the preferred cadence) at 200 W to test the hypothesis that electromyographic activity of selected lower limb muscles is minimized at the preferred cadence. Average preferred cadences for cyclists (85.2 +/- 9.2 rpm) and noncyclists (91.6(More)
PURPOSE To determine whether an association exists between peripheral comfort level, as reflected by differentiated RPE measures, and the preferred cadences of subjects who differed in cycling experience and fitness level. METHODS Twelve experienced cyclists (C), ten runners (R), and ten less-trained noncyclists (LT), all of whom were male, pedaled at(More)
BACKGROUND Chronic subclinical inflammation may contribute to impaired physical function in older adults; however, more data are needed to determine whether inflammation is a common mechanism for functional decline, independent of disease or health status. METHODS We examined associations between physical function and inflammatory biomarkers in 542 older(More)
The Lifestyle Interventions and Independence for Elders (LIFE) Study is a Phase III randomized controlled clinical trial (Clinicaltrials.gov identifier: NCT01072500) that will provide definitive evidence regarding the effect of physical activity (PA) on major mobility disability in older adults (70-89 years old) who have compromised physical function. This(More)
With age, loss of skeletal muscle mass (sarcopenia) results in decreased muscle strength and power. Decreased strength and power, in turn, are closely linked with declines in physical function. Preferred walking speed, a marker of physical function, is slower in older adults compared to young adults. Research suggests that older adults may walk slower as a(More)