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We consider prediction and uncertainty analysis for systems which are approximated using complex mathematical codes. Such models, implemented as computer codes, are often generic in the sense that byâ€¦ (More)

- Anthony O'Hagan
- Rel. Eng. & Sys. Safety
- 2006

The Bayesian approach to quantifying, analysing and reducing uncertainty in the application of complex process models is attracting increasing attention amongst users of such models. The range andâ€¦ (More)

- Leonardo S. Bastos, Anthony O'Hagan
- Technometrics
- 2009

Mathematical models, usually implemented in computer programs known as simulators, are widely used in all areas of science and technology to represent complex real-world phenomena. Simulators areâ€¦ (More)

- Borislava Mihaylova, Andrew Briggs, Anthony O'Hagan, Simon G. Thompson
- Health economics
- 2011

We review statistical methods for analysing healthcare resource use and costs, their ability to address skewness, excess zeros, multimodality and heavy right tails, and their ease for general use. Weâ€¦ (More)

In geostatistics it is common practice to assume that the underlying spatial process is stationary and isotropic, that is the spatial distribution is unchanged when the origin of the index set isâ€¦ (More)

- Anthony O'Hagan, Jeremy E. Oakley
- Rel. Eng. & Sys. Safety
- 2004

The challenge problems set out in Oberkampf, Helton, Joslyn, Wojtkiewicz and Ferson (this issue), hereafter referred to as OHJWF, raise a variety of interesting questions. The background to thisâ€¦ (More)

- Samer A. Kharroubi, John Edward Brazier, Jennifer Roberts, Anthony O'Hagan
- Journal of health economics
- 2007

This paper reports on the findings from applying a new approach to modelling health state valuation data. The approach applies a nonparametric model to estimate SF-6D health state utility valuesâ€¦ (More)

- Christopher J. McCabe, John R. T. Brazier, +4 authors Katherine Stevens
- Journal of health economics
- 2006

In this paper we report the estimation of conditional logistic regression models for the Health Utilities Index Mark 2 and the SF-6D, using ordinal preference data. The results are compared to theâ€¦ (More)

- Jim Chilcott, Christopher J. McCabe, +5 authors David H. Miller
- BMJ
- 2003

OBJECTIVE
To evaluate the cost effectiveness of four disease modifying treatments (interferon betas and glatiramer acetate) for relapsing remitting and secondary progressive multiple sclerosis in theâ€¦ (More)

- Marc C. Kennedy, Clive W. Anderson, Stefano Conti, Anthony O'Hagan
- Rel. Eng. & Sys. Safety
- 2006

In this paper we present a number of recent applications in which an emulator of a computer code is created using a Gaussian process model. Tools are then applied to the emulator to performâ€¦ (More)