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Temporal expression of regulatory and structural muscle proteins during myogenesis of satellite cells on isolated adult rat fibers.
Myogenic precursors in adult skeletal muscle (satellite cells) are mitotically quiescent but can proliferate in response to a variety of stresses including muscle injury. To gain furtherExpand
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Gene Expression Patterns of the Fibroblast Growth Factors and Their Receptors During Myogenesis of Rat Satellite Cells
Satellite cells are the myogenic precursors in postnatal muscle and are situated beneath the myofiber basement membrane. We previously showed that fibroblast growth factor 2 (FGF2, basic FGF)Expand
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The transition from proliferation to differentiation is delayed in satellite cells from mice lacking MyoD.
Satellite cells from adult rat muscle coexpress proliferating cell nuclear antigen and MyoD upon entry into the cell cycle, suggesting that MyoD plays a role during the recruitment of satelliteExpand
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Fibroblast Growth Factor Promotes Recruitment of Skeletal Muscle Satellite Cells in Young and Old Rats
Although the role of satellite cells in muscle growth and repair is well recognized, understanding of the molecular events that accompany their activation and proliferation is limited. In this study,Expand
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Cardiac length dependence of force and force redevelopment kinetics with altered cross-bridge cycling.
We examined the influence of cross-bridge cycling kinetics on the length dependence of steady-state force and the rate of force redevelopment (k(tr)) during Ca(2+)-activation at sarcomere lengthsExpand
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Familial hypertrophic cardiomyopathy mutations in troponin I (K183D, G203S, K206Q) enhance filament sliding.
A major cause of familial hypertrophic cardiomyopathy (FHC) is dominant mutations in cardiac sarcomeric genes. Linkage studies identified FHC-related mutations in the COOH terminus of cardiacExpand
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Thin filament near‐neighbour regulatory unit interactions affect rabbit skeletal muscle steady‐state force‐Ca2+ relations
The role of cooperative interactions between individual structural regulatory units (SUs) of thin filaments (7 actin monomers : 1 tropomyosin : 1 troponin complex) on steady‐state Ca2+‐activatedExpand
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Cross-bridge versus thin filament contributions to the level and rate of force development in cardiac muscle.
In striated muscle thin filament activation is initiated by Ca(2+) binding to troponin C and augmented by strong myosin binding to actin (cross-bridge formation). Several lines of evidence have ledExpand
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Investigation of thin filament near‐neighbour regulatory unit interactions during force development in skinned cardiac and skeletal muscle
Ca2+‐dependent activation of striated muscle involves cooperative interactions of cross‐bridges and thin filament regulatory proteins. We investigated how interactions between individual structuralExpand
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2-deoxy-ATP enhances contractility of rat cardiac muscle.
To investigate the kinetic parameters of the crossbridge cycle that regulate force and shortening in cardiac muscle, we compared the mechanical properties of cardiac trabeculae with either ATP orExpand
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