Anthony J Matthews

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BACKGROUND Accumulating evidence suggests that oxidative modification of lipoproteins may play a significant role in atherogenesis. In this study, we hypothesized that the iron chelator deferiprone (L1) would function as an antioxidant and decrease atherosclerosis progression. MATERIALS AND METHODS For the in vitro studies, human low-density lipoprotein(More)
The concentration and activity of cholesteryl ester transfer protein (CETP) is increased in plasma in hypercholesterolemic humans and in experimental animals fed cholesterol. While the concentration of lipo-proteins appears to be the major determinant of CETP activity, we have found previously that dietary measures and pharmacologic agents that alter their(More)
This paper describes the development of a second generation superconducting torsion balance to be used for a precision measurement of the Casimir force and a short range test of the inverse square law of gravity at 4.2 K. The instrument utilizes niobium (Nb) as the superconducting element and employs passive damping of the parasitic modes of oscillation.(More)
Immunoreactive trypsinogen (IRT) used in screening for cystic fibrosis is heterogeneous, poorly characterized, and displays marked matrix effects when incorporated into blood spots, making long-term control of assay calibration difficult. The cut-off required to select a fixed proportion of samples (0.5% for the UK protocol) for second-tier mutation(More)
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