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RIA of nonpregnant rat uterus extracts showed 0.68 +/- 0.08 pmol/g adrenomedullin (ADM) and 3.23 +/- 0.08 pmol/g calcitonin gene-related peptide (CGRP). In the pregnant (20 days gestation) uterus, the ADM content was 0.90 +/- 0.17 pmol/g, and CGRP could not be detected. ADM messenger RNA was detected at high levels in the uterus, with a 1.8-fold increase in(More)
Fusarium head blight (FHB), or head scab, is an economically important disease of wheat (Triticum aestivum L.). In developing FHB-resistant soft winter wheat cultivars, breeders have relied on phenotypic selection, marker assisted selection (MAS), or a combination of the two. The objectives of this study were to estimate heritability of resistance in a(More)
94 diabetic patients established on treatment with porcine (n = 47) or bovine (n = 47) insulin took part in a double-blind crossover trial, in which 6-week periods of treatment with the appropriate animal insulin were compared with periods of treatment with biosynthetic human insulin (BHI). 6 patients withdrew during the trial, in 3 cases because of(More)
Choline deficiency (CD) increases susceptability of (he rat liver to a number of hepatocellular carcinogens with a wide diversity of structure and potency. While severe CD results in micronodular cirrhosis and enhanced tumor induction, even a mild deficiency, without cirrhosis is sufficient to result in the increased carcinogenic response. The effects of CD(More)
Designing a robotic fish is a challenging endeavor due to the non-linear dynamics of underwater environments. In this paper , we present an evolutionary computation approach for designing the caudal fin of a carangiform robotic fish. Evolutionary experiments are performed in a simulated environment utilizing a mathematical model to approximate the(More)
Developing complex behaviors for aquatic robots is a difficult en- gineering challenge due to the uncertainty of an underwater environment. Neuroevolution provides one method of dealing with this type of problem. Artificial neural networks discern different conditions by mapping sensory input to responses, and evolutionary computation provides a training(More)
—In this paper, we apply evolutionary multiobjective optimization to the design of a robotic fish with a flexible caudal fin. Specifically, we use the NSGA-II algorithm to discover solutions (physical dimensions, flexibility, and control parameters) that optimize both swimming performance and power efficiency. The optimization is conducted in a custom(More)
Many robotic systems experience fluctuating dynamics during their lifetime. Variations can be attributed in part to material degradation and decay of mechanical hardware. One approach to mitigating these problems is to utilize an adaptive controller. For example, in model-free adaptive control (MFAC) a controller learns how to drive a system by continually(More)
The minimal hormonal requirements for inducing the ovine beta-lactoglobulin gene have been investigated using mammary gland explants from ewes in the first half of pregnancy. Quantification of beta-lactoglobulin mRNA showed that a combination of insulin, cortisol and prolactin was required to stimulate the expression of the gene and that this response could(More)