Anthony G. Dodge

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Extensive knowledge of microbial metabolism has been earned through more than a century of reductionist study. There is now basic understanding of how cultivated bacteria transduce the chemical energy of a growth substrate into the work and biosynthetic processes that underlie both survival and replication. This includes an appreciation that microorganisms(More)
Cyanuric acid hydrolase (CAH) catalyzes the hydrolytic ring-opening of cyanuric acid (2,4,6-trihydroxy-1,3,5-triazine), an intermediate in s-triazine bacterial degradation and a by-product from disinfection with trichloroisocyanuric acid. In the present study, an X-ray crystal structure of the CAH-barbituric acid inhibitor complex from Azorhizobium(More)
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