Sort by:

• Highly Influential Citations
• Citations
• Acceleration
• Velocity
• Recency

Learn More

cDNA cloning and sequence analysis of beta ig-h3, a novel gene induced in a human adenocarcinoma cell line after treatment with transforming growth factor-beta.

• John E Skonier, Michael G. Neubauer, Linda Madisen, Kristi L. Bennett, Gregory D. Plowman, Anthony F. Purchio
• DNA and cell biology
• 1992

Transforming growth factor-beta (TGF-beta) is capable of affecting the proliferation of many cell types. To identify novel genes whose protein products may mediate cellular responses to this factor,… (More)

Non-invasive imaging of GFAP expression after neuronal damage in mice

• Lingyun Zhu, Sylvie Ramboz, Duane D Hewitt, Landin Boring, David S. Grass, Anthony F. Purchio
• Neuroscience Letters
• 2004

Up-regulation of glial fibrillary acidic protein (GFAP) expression is often used as a surrogate marker of neuronal damage. We have created a transgenic mouse line that carries the luciferase gene… (More)

Mechanism of activation of latent recombinant transforming growth factor beta 1 by plasmin

• Russette M. Lyons, Larry E. Gentry, Anthony F. Purchio, Harold L. Moses
• The Journal of cell biology
• 1990

Medium conditioned by Chinese hamster ovary (CHO) cells transfected with the simian pre-pro-TGF beta 1 cDNA contains high levels of latent TGF beta 1. The amino-terminal region of the TGF beta 1… (More)

Induction of apoptosis in cultured hepatocytes and in regressing liver by transforming growth factor beta 1.

• F A Oberhammer, Meredith Pavelka, +4 authors Rolf Schulte-Hermann
• Proceedings of the National Academy of Sciences…
• 1992

In previous studies hepatocytes undergoing cell death by apoptosis but not normal hepatocytes in rat liver showed immunostaining for transforming growth factor beta 1 (TGF-beta 1). Staining was much… (More)

Inhibition of mammary duct development but not alveolar outgrowth during pregnancy in transgenic mice expressing active TGF-beta 1.

• Dortie Pierce, Michael D. Johnson, +6 authors Harold L. Moses
• Genes & development
• 1993

The transforming growth factors beta (TGFs-beta) are potent inhibitors of cell proliferation and are usually secreted in a latent form. TGF-beta 1, TGF-beta 2, and TGF-beta 3 are expressed in… (More)

Molecular events in the processing of recombinant type 1 pre-pro-transforming growth factor beta to the mature polypeptide.

• Larry E. Gentry, Mario N. Lioubin, Anthony F. Purchio, Hans Marquardt
• Molecular and cellular biology
• 1988

Recently, the simian type 1 transforming growth factor beta (TGF-beta 1) cDNA was expressed at high levels in Chinese hamster ovary (CHO) cells by dihydrofolate reductase-induced gene amplification… (More)

Beta IG-H3, a novel secretory protein inducible by transforming growth factor-beta, is present in normal skin and promotes the adhesion and spreading of dermal fibroblasts in vitro.

• Richard G. LeBaron, K I Bezverkov, Michael P Zimber, Richard S Pavelec, John E Skonier, Anthony F. Purchio
• The Journal of investigative dermatology
• 1995

We have previously identified a gene, beta ig-h3, which is highly induced in A549 cells (human lung adenocarcinoma) after growth arrest by transforming growth factor-beta. The beta ig-h3 gene encodes… (More)

Site-directed mutagenesis of cysteine residues in the pro region of the transforming growth factor beta 1 precursor. Expression and characterization of mutant proteins.

• A M Brunner, Hans Marquardt, A R Malacko, Mario N. Lioubin, Anthony F. Purchio
• The Journal of biological chemistry
• 1989

Three cysteine residues are located in the pro region of the transforming growth factor beta 1 (TGF-beta 1) precursor at amino acid positions 33, 223, and 225. Previous studies (Gentry, L. E.,… (More)

Molecular cloning and nucleotide sequence of the pestivirus bovine viral diarrhea virus.

• M S Colett, Roger M. Larson, Christopher. Gold, Daryld Strick, Dennis K Anderson, Anthony F. Purchio
• Virology
• 1988

The RNA genome of the cytopathic NADL isolate of bovine viral diarrhea virus (BVDV) has been molecularly cloned and the nucleotide sequence determined. The cloned sequence was 12,573 nucleotides in… (More)

NF-kappaB and not the MAPK signaling pathway regulates GADD45beta expression during acute inflammation.

• Ning Zhang, Muhammad H. Ahsan, Leanne Zhu, Lidia C Sambucetti, Anthony F. Purchio, David B. West
• The Journal of biological chemistry
• 2005

The GADD45 (growth arrest and DNA damage-inducible) family of genes is involved in the regulation of cell cycle progression and apoptosis. To study signaling pathways affecting GADD45beta expression… (More)

• ‹
• 1
• 2
• 3
• 4
• 5
• ›