Learn More
Constraint handling is one of the major concerns when applying genetic algorithms (GAs) to solve constrained optimization problems. This paper proposes to use the gradient information derived from the constraint set to systematically repair infeasible solutions. The proposed repair procedure is embedded into a simple GA as a special operator. Experiments(More)
BACKGROUND Chronic hepatitis B infection rates among Vietnamese-American adults range from 7 to 14%. Carriers of HBV are over 200 times more likely to develop liver cancer than non-carriers, and Vietnamese males have the highest liver cancer incidence rate of any ethnic group in the USA (41.8 per 100,000). Culturally and linguistically appropriate(More)
Attempts to activate partially purified preparations of the guanylyl cyclase-A (GC-A) receptor with atrial natriuretic peptide (ANP) have previously failed, leading to speculation that essential cofactors are lost during purification procedures. The receptor was modified to contain the FLAG epitope (DYKDDDDK), expressed in Sf9 cells, and purified to(More)
AIMS To examine the expression of extracellular matrix metalloprotease inducer (EMMPRIN) and matriptase in hepatocellular carcinoma (HCC) and to correlate this with tumour progression. METHODS AND RESULTS Immunohistochemical analysis of EMMPRIN and matriptase was performed on tissue microarrays of 122 cases of HCC with various histological grades and/or(More)
Under-representation of minority and female participants prompted the U.S. legislature to mandate the inclusion of women and minorities in federally funded research. Recruitment of minorities to participate in clinical trials continues to be challenging. Although Asian Americans constitute one of the major minority groups in the U.S., published literature(More)
—Ongoing, rapid advances in three-dimensional (3D) printing technology are making it inexpensive for lay people to manufacture 3D objects. However, the lack of tools to help non-technical users design interesting, complex objects represents a significant barrier preventing the public from benefiting from 3D printers. Previous work has shown that an(More)
The optimal shelter locations for the flood evacuation planning are studied in this paper. We assume that the authority can control the traffic in certain part of the network while the evacuees choose which shelter to go and by which route. The shelter location problem is posed as a Stackelberg game, consisting of the leader (authority) determining the(More)