Learn More
Minicolumns are thought to be the smallest cortical modules within the hierarchical organization of the isocortex. Several reports suggest alterations in minicolumnar morphometry may be involved in psychiatric disorders such as autism, dyslexia, and schizophrenia. Thus far anatomical studies of minicolumns have primarily relied on measurements of pyramidal(More)
In this paper we present an improved segmentation algorithm that recursively explores various thresholding levels until it reaches a termination criteria. This segmentation algorithm is based on earlier work adapting Otsu's thresholding approach to myelinated bundles of axons in cortical tissue. Experimentation using over 120 images has confirmed that this(More)
  • 1