Anoopindar K Ghuman

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OBJECTIVE High-flow humidified nasal cannula is often used to provide noninvasive respiratory support in children. The effect of high-flow humidified nasal cannula on effort of breathing in children has not been objectively studied, and the mechanism by which respiratory support is provided remains unclear. This study uses an objective measure of effort of(More)
BACKGROUND We sought to determine optimal methods of respiratory inductance plethysmography (RIP) flow calibration for application to pediatric postextubation upper airway obstruction. METHODS We measured RIP, spirometry, and esophageal manometry in spontaneously breathing, intubated Rhesus monkeys with increasing inspiratory resistance. RIP calibration(More)
OBJECTIVE To investigate the relationship of markers of oxygenation, PaO2/FIO2 ratio, SpO2/FIO2 ratio, oxygenation index, oxygen saturation index, and dead space (end tidal alveolar dead space fraction) with mortality in children with acute hypoxemic respiratory failure. DESIGN Retrospective. SETTING Single-center tertiary care pediatric intensive care(More)
OBJECTIVE To investigate differences in sepsis mortality between prepubertal and postpubertal males and females. STUDY DESIGN This was a retrospective review of the Virtual PICU Systems (VPS) database (including 74 pediatric intensive care units [PICUs]) for 2006-2008. We included prepubertal (aged 2-7 years) and postpubertal (aged 16-21 years) children(More)
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