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NPYFa, A Chimeric Peptide of Met‐Enkephalin, and NPFF Induces Tolerance‐Free Analgesia
NPYFa is proposed as a potent, long‐acting antinociceptor lacking tolerance development as well as a probe to study opioid analgesia and the associated complex mechanisms of tolerance development. Expand
YFa and analogs: investigation of opioid receptors in smooth muscle contraction.
YFa revealed its side-effect-free analgesic properties with regard to arrest of gastrointestinal transit and provided evidences for the involvement of κ and anti-opioid receptors in smooth muscle contraction. Expand