Annika Reintam

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INTRODUCTION There are no universally accepted diagnostic criteria for gastrointestinal failure in critically ill patients. In the present study we tested whether the occurrence of food intolerance (FI) and intra-abdominal hypertension (IAH), combined in a 5-grade scoring system for assessment of gastrointestinal function (the Gastrointestinal Failure [GIF](More)
BACKGROUND Gastrointestinal (GI) problems are not uniformly assessed in intensive care unit (ICU) patients and respective data in available literature are insufficient. We aimed to describe the prevalence, risk factors and importance of different GI symptoms. METHODS We prospectively studied all patients hospitalized to the General ICU of Tartu University(More)
INTRODUCTION Gastrointestinal failure (GIF) has been postulated as the motor of multiple organ dysfunction syndrome (MODS) but is not commonly included among other organ failures in scoring systems identifying MODS. MATERIALS AND METHODS Relevant articles and published reviews were identified and analyzed through a PubMed search of English language(More)
To investigate the differences in incidence, time course and outcome of primary versus secondary intra-abdominal hypertension (IAH), and to evaluate IAH as an independent risk factor of mortality in a presumable risk population of critically ill patients. Prospective observational study. General intensive care unit of a university hospital. A total of 257(More)
BACKGROUND While gastrointestinal problems are common in ICU patients with multiple organ failure, gastrointestinal failure has not been given the consideration other organ systems receive. The aim of this study was to evaluate the incidence of gastrointestinal failure (GIF), to identify its risk factors, and to determine its association with ICU mortality.(More)
Mouse N1E-115 neuroblastoma cells were used to study carbachol induced changes in muscarinic cholinergic parameters. Cells were treated with carbachol (1 mM) for up to 96 hours. The number of muscarinic receptors, measured in 3H-3-quinuclidinyl benzilate binding experiments, decreased approximately 50% after 4 hours exposure to carbachol. This was followed(More)
1Clinic of Anaesthesiology and Intensive Care, University of Tartu, Puusepa, Tartu 51014, Estonia 2Department of Anaesthesiology and Intensive Care, East Tallinn Central Hospital, Ravi, Tallinn 10138, Estonia 3Clinic of Anaesthesiology and Intensive Care, Tartu University Hospital, Puusepa, Tartu 51014, Estonia 4Klinik für Anästhesiologie und(More)