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Recombinant M2e outer membrane vesicle vaccines protect against lethal influenza A challenge in BALB/c mice.
Currently approved influenza vaccines predominantly protect through antibodies directed against the highly variable glycoprotein hemagglutinin (HA), necessitating annual redesign and formulation… Expand
Safe Recombinant Outer Membrane Vesicles that Display M2e Elicit Heterologous Influenza Protection.
- Hannah C. Watkins, C. Rappazzo, +11 authors D. Putnam
- Biology, Medicine
- Molecular therapy : the journal of the American…
- 5 April 2017
Recombinant, Escherichia coli-derived outer membrane vesicles (rOMVs), which display heterologous protein subunits, have potential as a vaccine adjuvant platform. One drawback to rOMVs is their… Expand
A single dose and long lasting vaccine against pandemic influenza through the controlled release of a heterospecies tandem M2 sequence embedded within detoxified bacterial outer membrane vesicles.
The influenza A virus undergoes genetic drift and shift, leaving the general population susceptible to emerging pandemic strains, despite seasonal flu vaccination. Here we describe a single dose… Expand
On Aristotle and Marx : A Critique of Aristotelian Themes in Marxist Labor Theory May 2003
This paper examines the influences of Aristotelian moral economic thought on Marx’s labor theory. This paper looks at certain moral ethical frameworks attributed to Aristotle and later used by Marx… Expand