Annick Jullienne

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Medullary thyroid cancer (MTC) is a C cell neoplasm-secreting calcitonin. Surgery remains the only treatment as the primary tumor and metastases resist radio- and chemotherapies. MTC produces high amounts of prostaglandins (PGs). Nonsteroidal antiinflammatory drugs have an antitumoral effect, generally related to the decrease of PG levels. We assessed the(More)
  • Pascale P Ghillani, Philippe Motté, Frédéric Troalen, Pascale P Chilian, Philippe Motte, Frã©dã©ric Troalen +7 others
  • 2006
Previous studies have suggested that molecular species larger than the mature calcitonin «I) are produced by tumors of different origin. In order to study these species, we developed a monoclonal immunoradi-ometric assay for calcitonin precursors (CT-pr). This assay was based on both monoclonal antibody KC01 directed to the 1-11 region of katacalcin and(More)
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