Annette M. Stolwijk

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OBJECTIVE To gain more insight into psychological aspects of dropping out from IVF-ICSI. DESIGN Prospective cohort study. SETTING University hospital-based tertiary care fertility clinic. PATIENT(S) Women entering their first treatment cycle of IVF or ICSI. INTERVENTION(S) Standardized psychological questionnaires were administered before the start(More)
The aim of this study was to create reliable models to predict the probability of achieving an ongoing pregnancy during in-vitro fertilization (IVF) treatment: model A, at the start of the first treatment, model B at the time of embryo transfer, and model C, during the second treatment at the end of the first IVF treatment. Prognostic models were created(More)
BACKGROUND The aim of this study was to investigate whether a pre-incubation time between oocyte retrieval and insemination or injection had any effect on the success rate of IVF or intracytoplasmic sperm injection (ICSI). Based on previously published data, many laboratories retain a time interval of several hours between oocyte retrieval and(More)
This study aimed to externally validate the prognostic model presented by Templeton in 1996 for live births resulting from IVF treatment. Data were used from the University Hospital, Nijmegen, The Netherlands, from March 1991 to January 1999. The predictive capacity of the model in our population discriminated between those women with a low probability of(More)
As most studies overestimate the cumulative pregnancy rate, a method is proposed to estimate a more realistic cumulative pregnancy rate by taking into account the reasons for an early cessation of treatment with in-vitro fertilization (IVF). Three methods for calculating cumulative pregnancy rates were compared. The first method assumed that those who(More)
The aim of this study was to estimate reliable cumulative probabilities of achieving an ongoing pregnancy after successive in-vitro fertilization or intracytoplasmic sperm injection (IVF/ICSI) cycles, according to a woman's age, subfertility diagnosis and primary or secondary subfertility. Therefore reasons for quitting treatment without achieving an(More)
STUDY OBJECTIVE A statistical test that allows for adjustment of confounding can be helpful for the study of seasonal patterns. The aim of this article is to supply a detailed description of such a method. An example of its application is given. DESIGN A statistical test is presented that retains the information on the connection of time periods by(More)
This study aimed to validate prognostic models for predicting ongoing pregnancy after the first and second in-vitro fertilization cycles. Models were developed using data from the University Hospital, Nijmegen, 1991-1994 and tested using more recent data from the same centre and data from two other centres. Although the variables included in the models(More)
OBJECTIVE To study the effect of the age of the woman who provides the oocytes or who receives the embryos on results of IVF-ET. DESIGN Historical cohort study. Multivariate regression analysis was used to study the age effect continuously and after adjustment for confounding. SETTING Patients of the University of Southern California, Los Angeles,(More)
To study seasonality in human fecundability, measured indirectly by time to the first pregnancy, we used data from 18,970 French-Canadian women who married for the first time during the 17th or 18th century. The time to pregnancy was approximated by the interval between marriage and first birth minus 38 weeks. We used the week of marriage and the week of(More)