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Seasonal malaria chemoprevention, previously known as intermittent preventive treatment in children, is highly effective in areas with a short malaria transmission season. Here we assess seasonality in malaria incidence data and define a predictor of seasonality based on rainfall. We then use spatial rainfall, malaria endemicity and population data to(More)
ach year across the US, mesoscale weather events—flash floods, tornadoes, hail, strong winds, lightning, and localized winter storms—cause hundreds of deaths, routinely disrupt transportation and commerce , and lead to economic losses averaging more than US$13 billion. 1 Although mitigating the impacts of such events would yield enormous economic and(More)
INTRODUCTION Insecticide-treated nets (ITNs) are one of the main interventions used for malaria control. However, these nets may also be effective against other vector borne diseases (VBDs). We conducted a systematic review and meta-analysis to estimate the efficacy of ITNs, insecticide-treated curtains (ITCs) and insecticide-treated house screening (ITS)(More)
Recommended vector control tools against malaria, such as long-lasting insecticidal nets (LLINs) and indoor residual spraying (IRS), mainly target mosquitoes that rest and feed on human hosts indoors. However, in some malaria-endemic areas, such as Southeast Asia and South America, malaria vectors primarily bite outdoors meaning that LLINs and IRS may be(More)
BACKGROUND Vector-borne diseases cause a significant proportion of the overall burden of disease across the globe, accounting for over 10 % of the burden of infectious diseases. Despite the availability of effective interventions for many of these diseases, a lack of resources prevents their effective control. Many existing vector control interventions are(More)
CONTEXT Medications are taken to ease, control or cure ailments. They are effective and safe if used correctly. In the elderly, disorders that occur as a result of ageing, frequently require treatment, resulting in increased use of medications. Polypharmacy is common among the elderly and although it can be therapeutic in nature, is linked to adverse events(More)
1. Abstract Time Series Data Server (TSDS) is a software package for implementing a server that provides fast super-setting, sub-setting, filtering, and uniform gridding of time series-like data. TSDS was developed to respond quickly to requests for long time spans of data. Data may be served from a fast database, typically created by aggregating granules(More)
BACKGROUND Intermittent preventive treatment of malaria in children less than five years of age (IPTc) has been investigated as a measure to control the burden of malaria in the Sahel and sub-Sahelian areas of Africa where malaria transmission is markedly seasonal. METHODS AND FINDINGS IPTc studies were identified using a systematic literature search.(More)
ach year across the US, mesoscale weather events—flash floods, tornadoes, hail, strong winds, lightning, and localized winter storms—cause hundreds of deaths, routinely disrupt transportation and commerce , and lead to economic losses averaging more than US$13 billion. 1 Although mitigating the impacts of such events would yield enormous economic and(More)