Learn More
Nitric oxide (NO), a multifaceted bioregulatory agent and an environmental pollutant, can also cause genomic alterations. In vitro, NO deaminated deoxynucleosides, deoxynucleotides, and intact DNA at physiological pH. That similar DNA damage can also occur in vivo was tested by treating Salmonella typhimurium strain TA1535 with three NO-releasing compounds,(More)
Histamine has been proposed as a photoreceptor neurotransmitter in two major groups of arthropods, the insects and the crustacea. In this study biochemical and immunocytochemical approaches were used to examine the synthesis, endogenous content, and cellular distribution of histamine in the visual system of the horseshoe crab Limulus polyphemus, an ancient(More)
OBJECTIVE The purpose of this study was to quantify the distribution of strength impairments soon after stroke. We were specifically interested in differences in impairments between proximal and distal actions, flexion and extension actions, and upper and lower limb actions. DESIGN We conducted a retrospective chart review of strength scores of patients(More)
Two raters performed hand-held dynamometer testing of six muscle groups of 30 patients to determine the interrater reliability of the procedure. The six muscle groups tested were the shoulder external rotators, elbow flexors, wrist extensors, hip flexors, knee extensors, and ankle dorsiflexors. The patients were of eight different diagnostic groups, with(More)
The photoreceptors of the horseshoe crab Limulus polyphemus are classical preparations for studies of the photoresponse and its modulation by circadian clocks. An extensive literature details their physiology and ultrastructure, but relatively little is known about their biochemical organization largely because of a lack of antibodies specific for Limulus(More)
BACKGROUND AND PURPOSE The extent of a patient's impairment can be established by comparing measurements of that patient's performance with normative values obtained from apparently unimpaired individuals. Only a few studies have described normative values for muscle strength measured by hand-held dynamometry. The purpose of this study of older adults,(More)
The effects of lithocholic acid on the mutagenicity of 24 aromatic amines in the Ames assay were examined. When lithocholic acid was added to the Salmonella/mammalian--microsome mutagenicity system with the use of postmitochondrial supernatant fractions from livers of male inbred SD rats pretreated with Aroclor 1254 or phenobarbital, various effects on the(More)
OBJECTIVES To document, by using norm-referenced strength measures, the recovery of limb muscle strength of patients undergoing stroke rehabilitation and to examine the relation between comorbidities and the recovery of strength after stroke. DESIGN Retrospective analysis of data from a consecutive convenience sample of patients examined clinically(More)
Eighteen compounds structurally related to the mutagenic carcinogen vinyl chloride have been tested for mutagenicity in five strains of Salmonella typhimurium. Acrolein, acrolein diethylacetal, acrylonitrile, allyl alcohol, allyl bromide, crotonaldehyde, crotyl alcohol, and vinyl bromide were mutagenic with one or more strains; acrolein bisulfite, acrolein(More)
Twenty-four patients with stroke were studied (a) to determine the interrater reliability of a clinical measurement of shoulder subluxation, (b) to confirm the interrater reliability of the Ritchie Articular Index (Bohannon & LeFort, 1986) for measuring shoulder pain, (c) to establish the relationship between the Ritchie index scores and shoulder lateral(More)