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  • Jörg König, Anne T Nies, Yuanyuan Cui, Inka Leier, Dietrich Keppler
  • Medicine, Biology
  • Biochimica et biophysica acta
  • 1999 (First Publication: 1 December 1999)
  • The membrane proteins mediating the ATP-dependent transport of lipophilic substances conjugated to glutathione, glucuronate, or sulfate have been identified as members of the multidrug resistanceExpand
  • Maria Dolores S. Rius, Anne T Nies, Johanna Hummel-Eisenbeiss, Gabriele Jedlitschky, Dietrich Keppler
  • Biology, Medicine
  • Hepatology
  • 2003 (First Publication: 1 August 2003)
  • The liver is the major source of reduced glutathione (GSH) in blood plasma. The transport protein mediating the efflux of GSH across the basolateral membrane of human hepatocytes has not beenExpand
  • Anne T Nies, Hermann Koepsell, +7 authors Elke Schaeffeler
  • Medicine, Biology
  • Hepatology
  • 2009 (First Publication: 1 October 2009)
  • UNLABELLED An important function of hepatocytes is the biotransformation and elimination of various drugs, many of which are organic cations and are taken up by organic cation transporters (OCTs) ofExpand
  • Christoph W. Michalski, Yunhai Cui, +7 authors Jörg König
  • Biology, Medicine
  • The Journal of Biological Chemistry
  • 2002 (First Publication: 8 November 2002)
  • The organic anion transporter SLC21A6 (also known as OATP2, OATP-C, or LST-1) is involved in the hepatocellular uptake of a variety of endogenous and xenobiotic substances and drugs. We analyzed 81Expand