Anne P. McGeorge

Learn More
The effects of phencyclidine on cerebral blood flow, cerebral metabolic rate for oxygen and carbon dioxide reactivity were compared with those of Althesin in six baboons. Under similar and stable levels (Stage 1) of electroencephalographic activity cerebral blood flow and the cerebral metabolic rate for oxygen were significantly less during the infusion of(More)
We present the results of single photon emission computed tomography (SPECT) in 40 patients with temporal lobe epilepsy and normal computed transmission tomography (CT). Abnormalities of regional cerebral blood flow were found in 26 patients. There was focal hypoperfusion alone in 14, focal hyperperfusion alone in 6, and both types of abnormality in 6. In 4(More)
The effect of intracarotid prostacyclin (PGI2) on cerebral blood flow (CBF) was measured by the 133xenon intracarotid injection technique in 8 baboons. Intracarotid prostacyclin increased CBF by 22% at 10(-7) g/kg/min and by 71% at 5 x 10(-6) g/kg/min, accompanied by systemic hypotension and tachycardia. The effects of PGI2 (10(-7) g/kg/min) were not(More)
A series of cervical myelograms performed by direct puncture resulted in almost identical incidence of side effects, more contrast within the skull, more frequent EEG abnormalities and only slightly better radiographic quality than in a comparable series of patients in whom the contrast was run up from the lumbar region.
Cranial computed tomography (CT) with modified temporal lobe technique, 0.15T magnetic resonance imaging (MRI) and single photon emission computed tomography (SPECT) were carried out on 30 patients with intractable temporal lobe epilepsy. Lateralising abnormalities were detected in 21/30 patients overall. Specific lesions were detected by CT in one patient(More)
A randomised double blind trial of iohexol and iopamidol in cervical myelography by both lumbar puncture and direct puncture techniques is reported in one hundred consecutive patients. All patients had EEG examination before and 6-8 h after the myelogram and for each a questionnaire regarding adverse reactions was completed at set intervals. The side(More)