Anne M. Owen

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A tetramer quadruplex structure is formed by four parallel strands of DNA/ RNA containing runs of guanine. These quadruplexes are able to form because guanine can Hoogsteen hydrogen bond to other guanines, and a tetrad of guanines can form a stable arrangement. Recently we have discovered that probes on Affymetrix GeneChips that contain runs of guanine do(More)
We discuss the applicability of the Microsoft cloud computing platform, Azure, for bioinformatics. We focus on the usability of the resource rather than its performance. We provide an example of how R can be used on Azure to analyse a large amount of microarray expression data deposited at the public database ArrayExpress. We provide a walk through to(More)
Cloud based scientific data management - storage, transfer, analysis, and inference extraction - is attracting interest. In this paper, we propose a next generation cloud deployment model suitable for data intensive applications. Our model is a flexible and self-service container-based infrastructure that delivers - network, computing, and storage resources(More)
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