Anne Le Quellec

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Probe calibrations are required for accurate estimations of extracellular concentrations in microdialysis experiments. Several methods have been developed and validated for in vivo determination of dialysis membrane recovery such as the perfusion rate method and the No Net Flux method. In this study, the No Net Flux and the reverse dialysis methods were(More)
Indocyanine green (ICG, CAS 3599-32-4) kinetics were used to assess hepatic function in rats with progressive hepatic disease induced by carbon tetrachloride administered by two different routes (intragastric and intraperitoneal). Four groups of animals with hepatic insufficiency (4, 6, 8, 10 weeks of intoxication) and two control groups (with or without(More)
Acamprosate, a stimulant of central inhibitory GABA neurotransmision and an antagonist of excitatory amino acids, is used in alcohol withdrawal and for the maintenance of abstinence. After identification of several cases of treatment discontinuation during alcohol abstinence because of acamprosate-induced adverse drug reactions (ADRs), a retrospective study(More)
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