Anne Giessler

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Quality of life is often severely impaired in people with schizophrenia, and adherence to antipsychotic medication has been consistently found to be low in this population. Although there is a considerable amount of evidence on these two variables in schizophrenia research, there is only limited knowledge on how they relate to one another. The aim of this(More)
Kappa-carrageenins cause disseminated intravascular coagulation with thrombosis of the tail in rats and mice. Frequency and extent of tail thrombosis were used for determining antithrombotic effects after systemic and local external administration of substances. Inhibitors of cyclooxygenase and thromboxane synthetase caused irregular inhibition of(More)
BACKGROUND Economic evaluations of healthcare interventions increasingly measure outcomes using quality-adjusted life years (QALYs). The SF-6D and the EQ-5D are alternative ways of generating utility scores for use in QALY estimations, but it is unclear which is most sensitive to change in psychiatric symptom severity. There are also limited data on the(More)
Among different carrageenins, kappa-carrageenins were found to be thrombogenic, whereas lambdacarrageenins were inactive in this respect, although the latter substances exerted a stronger edemogenic activity. Kappcarrageenin (Sigma) was the most potent thrombogen. As the consequence of thrombosis tail infarction became visible some minutes after i.v.(More)
predator which was previously thought to respond to the P. chalcographus pheromone, chalcogran, only [11]. Though nothing is known about the biosynthesis of pityol, some interesting structural relations to other pheromones may be discussed (see Fig. 4). Simple biotransformations of the widespread terpenoid, 6-methyl-5-hepten-2one (3), present in the(More)
Infusion of lysolecithin (LPC; e.g. 88 μg/ml for 0.5–1.0 min) did not significantly impair the vasopressor action of norepinephrine (NE), prostaglandin F2α (PGF2α) and extract of posterior pituitary (EPP) in the isolated perfused hind legs of rats. In other words, vascular smooth muscle behaves differently from the smooth muscle of the guinea-pig small(More)