Anne Georgiou

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PURPOSE Individuals who have been treated for breast cancer have been reported to have increased lymphocyte chromosomal sensitivity to ionizing radiation and a significantly lower apoptotic response to irradiation compared to controls. We set out to test these findings using a substantial number of cases sampled before treatment (which could alter the(More)
PURPOSE The impact of some technical factors on morbidity was analyzed in 738 patients with histologically confirmed carcinoma of the prostate treated with definitive irradiation. METHODS AND MATERIALS The records of all patients were reviewed, and morbidity of irradiation was evaluated according to severity. All patients were followed up for a minimum of(More)
There is conflicting evidence as to whether individuals who are heterozygous for germ-line BRCA1 or BRCA2 mutations have an altered phenotypic cellular response to irradiation. To investigate this, chromosome breakage and apoptotic response were measured after irradiation in peripheral blood lymphocytes from 26 BRCA1 and 18 BRCA2 mutation carriers without(More)
PURPOSE The purpose of this report is to evaluate the geometric movement (relative to the bony pelvis) of fixed brachytherapy reference points during the time interval of the first and second gynecologic intracavitary implant. METHODS AND MATERIALS The radiation therapy records of 40 consecutive patients with all stages of carcinoma of the cervix treated(More)
PURPOSE The influence of some tumor-related and technical factors on therapeutic outcome is analyzed in 738 patients with histologically confirmed carcinoma of the prostate treated with definitive irradiation. METHODS AND MATERIALS This is a retrospective study of the records of the Radiation Oncology Center. The information was coded on(More)
PURPOSE Radiation-induced lumbosacral plexopathy is a rare complication of pelvic irradiation. METHODS AND MATERIALS We report four cases among 2,410 patients treated to the pelvis for carcinoma of the cervix and carcinoma of the endometrium. All patients received both external beam and intracavitary radiation. The total calculated dose to the lumbosacral(More)
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