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Climate change is arguably the greatest challenge to conservation of our time. Most vulnerability assessments rely on past and current species distributions to predict future persistence but ignore species' abilities to disperse through landscapes, which may be particularly important in fragmented habitats and crucial for long-term persistence in changing(More)
A commonly observed preferential association was quantified between mature native mesquite (Prosopis articulata) trees and the seedlings of six cactus species (Pachycereus pringlei, Opuntia cholla, Lophocereus schottii, Machaerocereus gummo-sus, Lemaireocereus thurberi, Mammilaria sp.) in a previously-disturbed area of the Sonoran Desert of Baja California,(More)
Human pluripotent stem cells are a promising source of differentiated cells for developmental studies, cell transplantation, disease modeling, and drug testing. However, their widespread use even for intensely studied cell types like spinal motor neurons is hindered by the long duration and low yields of existing protocols for in vitro differentiation and(More)
This review examines the prevalence, associated morbidity, and treatment of primary dysmenorrhea in adolescent girls. Relevant literature was examined by systematic, evidence-based review using MEDLINE and Cochrane Collaboration databases. Dysmenorrhea is highly prevalent during adolescence. Despite differences in measurement methods, 20%-90% of adolescent(More)
STUDY OBJECTIVE To describe both non-pharmacologic and pharmacologic treatments used by adolescents with dysmenorrhea. DESIGN Cross-sectional study. SETTING Urban academic medical center. PARTICIPANTS Healthy adolescents aged 19 years or younger (n = 76) with moderate to severe primary dysmenorrhea were included; those using hormonal contraception(More)
OBJECTIVE To assess whether a low-dose oral contraceptive (OC) is more effective than placebo treatment for dysmenorrhea pain in adolescents. METHODS This was a randomized, double-blind, placebo-controlled clinical trial of 76 healthy adolescents aged 19 years or younger reporting moderate or severe dysmenorrhea. Subjects were randomly allocated to(More)
OBJECTIVE To evaluate the time to return to spontaneous menses in women after 1 year of daily continuous levonorgestrel (LNG) 90 microg/ethinyl E(2) (EE) 20 microg. DESIGN Observational study. SETTING Gynecologic and primary care practices. PATIENT(S) Women aged 18-49 years with a history of regular menstrual cycles. After participation in an(More)
BACKGROUND Many women discontinue their use of hormonal contraception, and even those who continue so may have difficulty using oral contraceptive pills consistently. New delivery systems, including the vaginal ring, may be easier to use, but user acceptability and satisfaction with these new methods may be affected by women's experience with their bodies.(More)
OBJECTIVE To report the contraceptive practices of women with epilepsy (WWE) in the community, predictors of highly effective contraception use, and reasons WWE provide for the selection of a particular method. METHODS These cross-sectional data come from the Epilepsy Birth Control Registry (EBCR) web-based survey regarding the contraceptive practices of(More)