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  • André Guillouzo, Anne Corlu, Caroline Aninat, Denise Glaise, Fabrice Morel, Christiane Guguen-Guillouzo
  • Chemistry, Medicine
  • Chemico-biological interactions
  • 2007 (First Publication: 1 May 2007)
  • Although they have several important limitations primary human hepatocytes still represent the in vitro gold standard model for xenobiotic metabolism and toxicity studies. The large use of humanExpand
  • Cédric Coulouarn, Anne Corlu, Denise Glaise, Isabelle Guénon, Snorri Thorgeirsson, Bruno Clement
  • Biology, Medicine
  • Cancer research
  • 2012 (First Publication: 15 May 2012)
  • Many solid malignant tumors arise on a background of inflamed and/or fibrotic tissues, features that are found in more than 80% hepatocellular carcinomas (HCC). Activated hepatic stellate cells (HSC)Expand
  • Madhushree Bhattacharya, Melina M. Malinen, +10 authors Marjo Yliperttula
  • Medicine, Chemistry
  • Journal of controlled release : official journal…
  • 2012 (First Publication: 28 December 2012)
  • Over the recent years, various materials have been introduced as potential 3D cell culture scaffolds. These include protein extracts, peptide amphiphiles, and synthetic polymers. Hydrogel scaffoldsExpand
  • Claire Legendre, Tamaki Hori, +8 authors Fabrice Morel
  • Biology, Medicine
  • European journal of cancer
  • 2009 (First Publication: 1 November 2009)
  • Weak blood irrigation within solid tumours including hepatocellular carcinomas (HCCs) plays an important role in resistance to anticancer drugs by decreasing accessibility of cytotoxic agents toExpand