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  • Constance E. Runyan, H. William Schnaper, Anne-Christine Poncelet
  • Biology, Medicine
  • The Journal of biological chemistry
  • 4 March 2005
  • Recent data investigating the role of the Smad anchor for receptor activation (SARA) in TGF-beta signaling have suggested that it has a crucial function in both aiding the recruitment of Smad to theContinue Reading
  • Tomoko Hayashida, Ming-hua Wu, Amy Pierce, Anne-Christine Poncelet, J. Kelemenne Varga, H. William Schnaper
  • Biology, Medicine
  • Journal of cell science
  • 1 December 2007
  • The signals mediating transforming growth factor beta (TGFbeta)-stimulated kidney fibrogenesis are poorly understood. We previously reported TGFbeta-stimulated, Smad-mediated collagen production byContinue Reading
  • Constance E. Runyan, H. William Schnaper, Anne-Christine Poncelet
  • Medicine
  • The Journal of biological chemistry
  • 2004
  • Transforming growth factor (TGF)-beta has been associated with renal glomerular matrix accumulation. We previously showed that Smad3 promotes COL1A2 gene activation by TGF-beta1 in human glomerularContinue Reading
  • Anne-Christine Poncelet, H. William Schnaper, Ruoyun Tan, Youhua Liu, Constance E. Runyan
  • Biology, Medicine
  • The Journal of biological chemistry
  • 25 May 2007
  • Signaling by transforming growth factor-beta (TGF-beta), a regulator of several biological processes, including renal fibrosis, is mediated, in part, by the Smad proteins. Tight control of Smad levelContinue Reading