Anne C Loughrey

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OBJECTIVES During 2003, the Health Protection Agency's Antibiotic Resistance Monitoring and Reference Laboratory began to receive isolates of Escherichia coli for confirmation of extended-spectrum beta-lactamase production with a phenotype implying a CTX-M-type beta-lactamase, i.e. MICs of cefotaxime > or = 8-fold higher than MICs of ceftazidime. Many were(More)
BACKGROUND To assess the prevalence and risk factors for faecal carriage of fluoroquinolone-resistant, extended-spectrum beta-lactamase (ESBL)-producing, Escherichia coli (MDR E. coli) among residents in nursing homes in Northern Ireland. METHODS Between January 2004 and May 2006, retrospective histories of hospital admissions, antimicrobial treatment and(More)
OBJECTIVES Between January 2004 and May 2006 Escherichia coli producing extended-spectrum β-lactamases (ESBLs) were isolated from the faeces of 118/294 residents from 16 nursing homes in Belfast. Of these, 58 isolates belonged to UK strain A, a variant of the international ST131 clone. Here we investigated the remaining 60 ESBL producers. METHODS MICs(More)
A new type of meticillin-resistant Staphylococcus aureus (MRSA) is emerging as a significant pathogen in otherwise healthy individuals in the community. This MRSA is distinct from healthcare-associated (HA)-MRSA, in terms of epidemiology, microbiology and clinical manifestations. A considerable number of reports are beginning to appear describing the(More)
BACKGROUND The aim of this study was to examine the survival dynamics of several epidemic nosocomial and community-acquired methicillin-resistant Staphylococcus aureus (MRSA) strains on copper alloy coins. METHODS Six different phage types of nosocomial MRSA (Irish 1, Irish 2, EMRSA 15, EMRSA 16, distinct type, and untypeable), as well as(More)
The aim of this study was to examine the survival dynamics of several epidemic healthcare (HA) and community-associated (CA) meticillin-resistant Staphylococcus aureus (MRSA) in river, sea and swimming pool waters. Six different phage-types of HA-MRSA (Irish 1, Irish 2, EMRSA 15, EMRSA 16, distinct type and non-typable), as well as a community-associated(More)
This well-established text-book, now in its Third edition, provides an attractive, authorative and integrated review of organ function and systems interactions in the normal body. The authors have two particular aims – to emphasise cellular physiology and to discuss the relevance of normal function to disturbed organ function or patho-physiology. The clear(More)
Polymerase chain reaction amplification of the universal 16S ribosomal RNA (rRNA) gene was performed on a collection of 38 bacterial isolates, originating from air sampled immediately adjacent to the agricultural spreading of bovine slurry. A total of 16 bacterial genera were identified including both Gram-positive and Gram-negative genera. Gram-positive(More)