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OBJECTIVES During 2003, the Health Protection Agency's Antibiotic Resistance Monitoring and Reference Laboratory began to receive isolates of Escherichia coli for confirmation of extended-spectrum beta-lactamase production with a phenotype implying a CTX-M-type beta-lactamase, i.e. MICs of cefotaxime > or = 8-fold higher than MICs of ceftazidime. Many were(More)
A new type of meticillin-resistant Staphylococcus aureus (MRSA) is emerging as a significant pathogen in otherwise healthy individuals in the community. This MRSA is distinct from healthcare-associated (HA)-MRSA, in terms of epidemiology, microbiology and clinical manifestations. A considerable number of reports are beginning to appear describing the(More)
BACKGROUND To assess the prevalence and risk factors for faecal carriage of fluoroquinolone-resistant, extended-spectrum beta-lactamase (ESBL)-producing, Escherichia coli (MDR E. coli) among residents in nursing homes in Northern Ireland. METHODS Between January 2004 and May 2006, retrospective histories of hospital admissions, antimicrobial treatment and(More)
Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) has now been described globally, as a clinically significant pathogen, particularly associated with skin and soft tissue infections, including abscesses, cellulitis and furunculosis. The recent emergence of CA-MRSA combined with its predominant presentation associated with skin and(More)
Polymerase chain reaction amplification of the universal 16S ribosomal RNA (rRNA) gene was performed on a collection of 38 bacterial isolates, originating from air sampled immediately adjacent to the agricultural spreading of bovine slurry. A total of 16 bacterial genera were identified including both Gram-positive and Gram-negative genera. Gram-positive(More)
OBJECTIVES Between January 2004 and May 2006 Escherichia coli producing extended-spectrum β-lactamases (ESBLs) were isolated from the faeces of 118/294 residents from 16 nursing homes in Belfast. Of these, 58 isolates belonged to UK strain A, a variant of the international ST131 clone. Here we investigated the remaining 60 ESBL producers. METHODS MICs(More)
The popularity of open farms and petting zoos has increased markedly over the last 5 years, with most children in developed countries now having the opportunity to visit such a facility at some stage in their childhood, either through school or family visits. The open access policy of these establishments allows visitors to be in direct contact with animals(More)
The aim of this study was to examine the survival dynamics of several epidemic healthcare (HA) and community-associated (CA) meticillin-resistant Staphylococcus aureus (MRSA) in river, sea and swimming pool waters. Six different phage-types of HA-MRSA (Irish 1, Irish 2, EMRSA 15, EMRSA 16, distinct type and non-typable), as well as a community-associated(More)
BACKGROUND The aim of this study was to examine the survival dynamics of several epidemic nosocomial and community-acquired methicillin-resistant Staphylococcus aureus (MRSA) strains on copper alloy coins. METHODS Six different phage types of nosocomial MRSA (Irish 1, Irish 2, EMRSA 15, EMRSA 16, distinct type, and untypeable), as well as(More)