Anne Bellemain

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BACKGROUND Clopidogrel loading has mostly been studied in clopidogrel-naïve patients. Whether clopidogrel-treated patients readmitted for an acute coronary syndrome or percutaneous coronary intervention can benefit from a new load of clopidogrel and at what dose remain unknown. Our aim was to evaluate the impact of 3 different strategies of administration(More)
Thienopyridines have become the cornerstone of treatment of percutaneous coronary intervention although no survival benefit has ever been shown with clopidogrel despite increasing loading doses. Newly developed P2Y(12) inhibitors are more potent, more predictable and have a faster onset of action than clopidogrel, characteristics that make them particularly(More)
We report a bilateral tension pneumothorax which occurred in a 36-year-old man after high-frequency jet ventilation (HFJV) for panendoscopy. The patient had been treated with radiotherapy and chemotherapy two years ago for an oropharyngeal adenocarcinoma, and by surgery for a recurrence. The incident occurred after a cough episode triggered by the(More)
Platelet-aggregation inhibitors are the cornerstone of the treatment and prevention of atherothrombotic events. Long limited to aspirin alone, new drugs have appeared in the past two decades. But only very recently have new targets been developed. The synergy of their mechanisms of action now makes it possible to obtain ever stronger inhibition of platelet(More)
Percutaneous coronary interventions of saphenous vein grafts are associated with an increased risk of periprocedural complications; among these, the rupture of the vein graft is probably the less common and the most dangerous; it is even more exceptional when it occurs on a stented portion of the graft. We report the case of a 75-year-old man who presented(More)
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