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Atrial fibrillation (AF) is the most common sustained arrhythmia and a major global public health problem due to its associated morbidity, including stroke and heart failure, diminished quality of life, and increased mortality. AF often presents initially in a paroxysmal form and may progress to a more sustained form over time. Evidence from randomized(More)
OBJECTIVE To determine the minimum prevalence of spinocerebellar ataxia type 17 (SCA17) in the north east of England. PATIENTS AND METHODS A defined region containing 2,516,500 individuals with 192 families with undiagnosed ataxia, 90 patients with a Huntington's disease-like phenotype and 292 controls. The number of (CAG/CAA)(n) repeats in the SCA17/TBP(More)
Sudden cardiac death (SCD) is a serious public health problem; the annual incidence of out-of-hospital cardiac arrest in North America is approximately 166,200. Identifying patients at risk is a difficult proposition. At the present time, left ventricular ejection fraction (LVEF) remains the single most important marker for risk stratification. According to(More)
BACKGROUND Several therapies are guideline-recommended to reduce mortality in patients with heart failure (HF) and reduced left ventricular ejection fraction, but the incremental clinical effectiveness of these therapies has not been well studied. We aimed to evaluate the individual and incremental benefits of guideline-recommended HF therapies associated(More)
This study compared the levels of conceptual responses involved in the processing of two parameters of social cognition in a group of 40 adult patients with closed-head injury (CHI) and a group of 26 normal controls. The two parameters, interpersonal negotiation strategies (INS) and self understanding (self) were examined in the framework of Selman's model(More)
BACKGROUND Faculty productivity is essential for academic medical centers striving to achieve excellence and national recognition. The objective of this study was to evaluate whether and how academic Departments of Medicine in the United States measure faculty productivity for the purpose of salary compensation. METHODS We surveyed the Chairs of academic(More)
Longevity is increasing and the population of older adults is growing. The biology of aging is conducive to cardiovascular disease (CVD), such that prevalence of coronary artery disease, heart failure, valvular heart disease, arrhythmia and other disorders are increasing as more adults survive into old age.  Furthermore, CVD in older adults is distinctive,(More)
BACKGROUND There is sufficient evidence that monetary incentives are effective in increasing survey response rates in the general population as well as with physicians. The objective of this study was to assess the impact of a monetary incentive intended for administrative assistants on the survey response rate of physicians in leadership positions. (More)
  • Kristan Lee Corwin, E Carl, Deborah S Wieman, Jin, Kristan Corwin, Lee +77 others
  • 1999
Date The final copy of this thesis has been examined by the signatories, and we find that both the content and the form meet acceptable presentation standards of scholarly work in the above mentioned discipline. Several innovations in laser trapping and cooling of alkali atoms are described. These topics share a common motivation to develop techniques for(More)
The evoked potential, the intracardiac signal generated by a pacing stimulus, shows promise as a sensor for rate-responsive pacing and automatic threshold determinations. Thus, it is important to understand factors that may alter the morphology of evoked potentials and affect accurate signal analysis. Using a computer-based pacing system emulator, stimuli(More)
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