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The association of reproductive factors with hormone receptor (HR)-negative breast tumors remains uncertain. Within the EPIC cohort, Cox proportional hazards models were used to describe the relationships of reproductive factors (menarcheal age, time between menarche and first pregnancy, parity, number of children, age at first and last pregnancies, time(More)
Genetic polymorphisms in vitamin D metabolism and signaling genes have been inconsistently associated with risk of breast cancer, though few studies have examined SNPs in vitamin D-related genes other than the vitamin D receptor (VDR) gene and particularly have not examined the association with the retinoid X receptor alpha (RXRA) gene which may be a key(More)
All things are poison and nothing is without poison, only the dose permits something not to be poisonous. Table of contents ll Abstract lll Abbreviations V Svensk populärvetenskaplig sammanfattning Vll Original papers Xl Introduction 1 Cancer – epidemiology and aetiology 1 Chemotherapy (CT) 2 Radiotherapy (RT) 3 Hodgkin's lymphoma 4 Treatment of Hodgkin's(More)
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