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  • Barbara Viviani, Stefano Bartesaghi, +8 authors Marina Marinovich
  • Biology, Medicine
  • The Journal of Neuroscience
  • 2003 (First Publication: 24 September 2003)
  • Interleukin (IL)-1β is a proinflammatory cytokine implicated in various pathophysiological conditions of the CNS involving NMDA receptor activation. Circumstantial evidence suggests that IL-1β andContinue Reading
  • Teresa Ravizza, Barbara Gagliardi, Francesco M. Noe, Karin Boer, Annamaria Vezzani
  • Biology, Medicine
  • Neurobiology of Disease
  • 2008
  • We investigated the activation of the IL-1 beta system and markers of adaptive immunity in rat brain during epileptogenesis using models of temporal lobe epilepsy (TLE). The same inflammatory markersContinue Reading
  • Annamaria Vezzani, Mirko Conti, +4 authors Maria Grazia De Simoni
  • Medicine, Biology
  • The Journal of Neuroscience
  • 1999 (First Publication: 15 June 1999)
  • Using immunocytochemistry and ELISA, we investigated the production of interleukin (IL)-1β in the rat hippocampus after focal application of kainic acid inducing electroencephalographic (EEG)Continue Reading
  • Annamaria Vezzani, Daniela Moneta, +9 authors Tamás Bartfai
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 2000 (First Publication: 10 October 2000)
  • IL-1beta and its endogenous receptor antagonist (IL-1Ra) are rapidly induced by seizures in the rodent hippocampus. Exogenously applied IL-1beta prolongs seizures in an IL-1R type I-mediated manner.Continue Reading